ELUVIXTAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	6Z4B5PJ4OP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ELUVIXTAMAB

Official Name

English

AMG-330

Preferred Name

English

IMMUNOGLOBULIN, ANTI-(HUMAN SIALIC ACID-BINDING IG-LIKE LECTIN 3) (HUMAN MONOCLONAL 1803MNGSSMABC SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSI

Common Name

English

A CD33/CD3 BISPECIFIC T-CELL ENGAGER ANTIBODY FOR ACUTE MYELOID LEUKEMIA THERAPY

Common Name

English

eluvixtamab [INN]

Common Name

English

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Classification Tree

Code System

Code

Designated

FDA ORPHAN DRUG

691519

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Code System

Code

Type

Description

USAN

JK-133

PRIMARY

FDA UNII

6Z4B5PJ4OP

PRIMARY

SMS_ID

300000028757

PRIMARY

CAS

1679391-73-1

PRIMARY

NCI_THESAURUS

C123332

PRIMARY

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Subunit 0

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From	To
1_22	1_96
1_160	1_231
1_278	1_354
1_418	1_486

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Related Record

Type

Details


					1U72JD9DDZ

T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN

TARGET -> ACTIVATOR

Amount:


					HX0GZ7OLW5

MYELOID CELL SURFACE ANTIGEN CD33

TARGET->LIGAND

Amount:

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Related Record

Type

Details


					6Z4B5PJ4OP

ACTIVE MOIETY

Amount:

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 54300 Da (average)
Molecular Formula	CHEMICAL	ESTIMATED C2396H3618O763N658S15

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