Crusekitug

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:52:49 GMT 2025` Edited by `admin` on `Wed Apr 02 20:52:49 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED RABBIT
Sequence Type	COMPLETE
Record UNII	6YYC67U8QJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

QX-002N

Preferred Name

English

Crusekitug

Official Name

English

crusekitug [INN]

Common Name

English

QX002N

Code

English

H-gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV4-4*08 (79.4%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.7.14] (26-33.51-57.96-109)) (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (217) (121-218), hinge 1-15 (219-

Common Name

English

Immunoglobulin G1, anti-(human interleukin 17A) (human-Oryctolagus cuniculus monoclonal QX002N ?1-chain), disulfide with human-Oryctolagus cuniculus monoclonal QX002N ?-chain, dimer

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens IL17A (interleukin 17A, IL-17A)], humanized monoclonal antibody

Common Name

English

Code System Code Type Description

FDA UNII

6YYC67U8QJ

Created by admin on Wed Apr 02 20:52:49 GMT 2025 , Edited by admin on Wed Apr 02 20:52:49 GMT 2025

PRIMARY

INN

13525

Created by admin on Wed Apr 02 20:52:49 GMT 2025 , Edited by admin on Wed Apr 02 20:52:49 GMT 2025

PRIMARY

CAS

2956768-50-4

Created by admin on Wed Apr 02 20:52:49 GMT 2025 , Edited by admin on Wed Apr 02 20:52:49 GMT 2025

PRIMARY

From	To
1_22	1_95
2_22	2_95
2_147	2_203
2_223	4_217
2_264	2_324
1_147	1_203
2_370	2_428
3_23	3_88
3_137	3_197
4_23	4_88
4_137	4_197
1_223	3_217
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					R44E6C7B6J

INTERLEUKIN-17A

TARGET->LIGAND

Amount:

Related Record Type Details


					6YYC67U8QJ

Crusekitug

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS	K		LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL