Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C30H55N5O3.CH4O3S |
| Molecular Weight | 629.895 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CS(O)(=O)=O.CCCCCCCCCCCCNCC(O)CCCCCCCCCN1C(=O)N(C)C2=C(N(C)C=N2)C1=O
InChI
InChIKey=RCBJUJRVBGYTEO-UHFFFAOYSA-N
InChI=1S/C30H55N5O3.CH4O3S/c1-4-5-6-7-8-9-10-13-16-19-22-31-24-26(36)21-18-15-12-11-14-17-20-23-35-29(37)27-28(32-25-33(27)2)34(3)30(35)38;1-5(2,3)4/h25-26,31,36H,4-24H2,1-3H3;1H3,(H,2,3,4)
| Molecular Formula | CH4O3S |
| Molecular Weight | 96.106 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C30H55N5O3 |
| Molecular Weight | 533.7894 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
CT-2584 is a cytotoxic agent which modulates intracellular metabolism of phosphatidic acid in tumor cells. CT-2884 inhibits CTP:choline-phosphate cytidylyltransferase and causes de novo phospholipid biosynthesis via phosphatidic acid to be shunted away from phosphatidylcholine and into phosphatidylinositol. CT-2884 induced cytotoxicity is associated with disruption and swelling of endoplasmic reticulum and mitochondria. In the early 2000s, CT-2584 was investigated in phase 2 clinical trials for the treatment of prostate cancer and soft-tissue sarcoma. No development of the drug was reported since.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:59:35 GMT 2023
by
admin
on
Fri Dec 15 15:59:35 GMT 2023
|
| Record UNII |
6YX1G1VY8K
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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FDA ORPHAN DRUG |
124899
Created by
admin on Fri Dec 15 15:59:35 GMT 2023 , Edited by admin on Fri Dec 15 15:59:35 GMT 2023
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|
FDA ORPHAN DRUG |
125899
Created by
admin on Fri Dec 15 15:59:35 GMT 2023 , Edited by admin on Fri Dec 15 15:59:35 GMT 2023
|
||
|
FDA ORPHAN DRUG |
121798
Created by
admin on Fri Dec 15 15:59:35 GMT 2023 , Edited by admin on Fri Dec 15 15:59:35 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
71587716
Created by
admin on Fri Dec 15 15:59:35 GMT 2023 , Edited by admin on Fri Dec 15 15:59:35 GMT 2023
|
PRIMARY | |||
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6YX1G1VY8K
Created by
admin on Fri Dec 15 15:59:35 GMT 2023 , Edited by admin on Fri Dec 15 15:59:35 GMT 2023
|
PRIMARY | |||
|
C202251
Created by
admin on Fri Dec 15 15:59:35 GMT 2023 , Edited by admin on Fri Dec 15 15:59:35 GMT 2023
|
PRIMARY | |||
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353525-62-9
Created by
admin on Fri Dec 15 15:59:35 GMT 2023 , Edited by admin on Fri Dec 15 15:59:35 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |