BENZAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H7NO
Molecular Weight	121.1366
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)C1=CC=CC=C1

InChI

InChIKey=KXDAEFPNCMNJSK-UHFFFAOYSA-N

InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)

HIDE SMILES / InChI

Molecular Formula	C7H7NO
Molecular Weight	121.1366
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The Gal4 activation domain binds Sug2 protein, a proteasome component, in vivo and in vitro.	2001-08-17	11418596
Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides.	2001-07-25	11423351
Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties.	2001-07-09	11425561
Synthesis of substituted 5[H]phenanthridin-6-ones as potent poly(ADP-ribose)polymerase-1 (PARP1) inhibitors.	2001-07-09	11425538
Discovery of novel mesangial cell proliferation inhibitors using a three-dimensional database searching method.	2001-07-05	11428924
Novel N-(arylalkyl)indol-3-ylglyoxylylamides targeted as ligands of the benzodiazepine receptor: synthesis, biological evaluation, and molecular modeling analysis of the structure-activity relationships.	2001-07-05	11428922
R-zacopride, a 5-HT3 antagonist/5-HT4 agonist, reduces sleep apneas in rats.	2001-06-23	11420096
Determination of five pesticide residues in oranges by matrix solid-phase dispersion and liquid chromatography to estimate daily intake of consumers.	2001-06-22	11417653
Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design.	2001-06-21	11405646
Opioid peptide receptor studies. 15. Relative efficacy of 4-[(N-allyl-3-methyl-4-piperidinyl)phenylamino]-N,N-diethylbenzamide and related compounds at the cloned human delta-opioid receptor.	2001-06-15	11309842
Selective up-regulation of 5-HT(1B/1D) receptors during organ culture of cerebral arteries.	2001-06-13	11409725
Site-directed mutagenesis of the 5-HT1B receptor increases the affinity of 5-HT for the agonist low-affinity conformation and reduces the intrinsic activity of 5-HT.	2001-06-08	11399261
Updated information for treatment of fungal infections in cats and dogs.	2001-06-01	11394811
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.	2001-06	11428523
Carboxymethyl benzylamide dextran and tamoxifen combination inhibits tumor growth and angiogenesis.	2001-06	11410523
Synthesis, molecular modeling and QSAR studies in chiral 2,3-disubstituted-1,2,3,4-tetrahydro-9H-pyrido(3,4-b)indoles as potential modulators of opioid antinociception.	2001-06	11408175
Studies on selectin blocker. 9. SARs of non-sugar selectin blocker against E-, P-, L-selectin bindings.	2001-06	11408166
Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors.	2001-06	11406192
Alkaloids from Haplophyllum tuberculatum.	2001-06	11394865
Dopamine D(2) receptor blockade in schizophrenia.	2001-06	11384924
LC determination of Z-338, novel gastroprokinetic agent in dog plasma by SCX solid phase extraction.	2001-06	11377040
p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis.	2001-05-15	11331359
A new class of cytotoxic DNA minor groove binders: alpha-halogenoacrylic derivatives of pyrrolecarbamoyl oligomers.	2001-05-12	11347968
Anticoagulant properties of dextranmethylcarboxylate benzylamide sulfate (DMCBSu); a new generation of bioactive functionalized dextran.	2001-05-08	11403090
Discrimination between peptide and non-peptide opioid agonists on the transcription of opioid receptors in two cell lines.	2001-05-04	11400915
Increased tumor necrosis factor-alpha and nitric oxide production by rat macrophages following in vitro stimulation and intravenous administration of the delta-opioid agonist SNC 80.	2001-05-04	11400911
Oral agents in the management of type 2 diabetes mellitus.	2001-05-01	11352285
Phenylamides of 1-phenyl (or methyl)-5-benzamidopyrazole-4-carboxylic acid as vratizolin analogs with analgesic and antiinflammatory activities.	2001-05	11413820
Comparison of in vivo dopamine D2 receptor binding of [(123)I]AIBZM and [(123)I]IBZM in rat brain.	2001-05	11395310
Opposite effects of antidepressants and corticosterone on the sensitivity of hippocampal CA1 neurons to 5-HT1A and 5-HT4 receptor activation.	2001-05	11383709
Amino acid derivatives with anticonvulsant activity.	2001-05	11383620
Suppression of the radiation-sensitive phenotype of hamster irs1 and irs2 strains selected for resistance to 3-aminobenzamide.	2001-05	11382339
Herbicidal properties of the thaxtomin group of phytotoxins.	2001-05	11368592
Sarcolemmal and mitochondrial K(atp)channels mediate cardioprotection in chronically hypoxic hearts.	2001-05	11343425
Dopamine D(2)/D(3)-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics.	2001-05	11326293
Effects of yohimbine on the antinociceptive and place conditioning effects of opioid agonists in rodents.	2001-05	11325807
High-performance liquid chromatography-electrospray ionization mass spectrometry method for the measurement of moclobemide and two metabolites in plasma.	2001-04-25	11339275
Spinal delta-opioid receptors mediate suppression of systemic SNC80 on excitability of the flexor reflex in normal and inflamed rat.	2001-04-20	11334868
Mutation W284L of the human delta opioid receptor reveals agonist specific receptor conformations for G protein activation.	2001-04-06	11358332
A quantum-mechanical description of macrocyclic ring rotation in benzylic amide.	2001-04-01	11330899
Mouse macrophages release a neutrophil chemotactic mediator following stimulation by staphylococcal enterotoxin type A.	2001-04	11392608
Involvement of cortical microtubules in plastic extension regulated by gibberellin in Lemna minor root.	2001-04	11333310
Bait matrix for delivery of chitin synthesis inhibitors to the formosan subterranean termite (Isoptera: Rhinotermitidae).	2001-04	11332846
Synthesis and gastrointestinal prokinetic activity of novel benzamide derivatives with amphoteric side chains.	2001-04	11310669
Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19.	2001-04	11309556
Role of p38 MAP kinase in LPS-induced airway inflammation in the rat.	2001-04	11309243
Relaxation induced by serotonin and sumatriptan in isolated guinea pig gallbladder strips.	2001-03	11426669
Rat germinal cells require PARP for repair of DNA damage induced by gamma-irradiation and H2O2 treatment.	2001-03	11322386
The formation of 2-chlorobenzamide upon hydrolysis of the benzoylphenylurea insecticide 1-(2-chlorobenzoyl)-3-(4-chlorophenyl) urea in different water systems.	2001-03	11312855
Kinetic dependence of the aqueous reaction of N-(hydroxymethyl)benzamide derivatives upon addition of electron-withdrawing groups.	2001-01-11	11429876

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:34:42 GMT 2025` Edited by `admin` on `Mon Mar 31 18:34:42 GMT 2025`
Record UNII	6X80438640
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BENZAMIDE

Systematic Name

English

NSC-3114

Preferred Name

English

BENZENECARBOXAMIDE

Systematic Name

English

BENZAMIDE [MI]

Common Name

English

BENZAMIDE [HSDB]

Common Name

English

Code System Code Type Description

WIKIPEDIA

BENZAMIDE