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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 10:45:24 GMT 2025
Edited
by admin
on Wed Apr 02 10:45:24 GMT 2025
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Type COMPLETE
Record UNII
6W6Z6G78V3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Immunoglobulin G1 [299-alanine], anti-(human programmed death-ligand 1) (human-Mus musculus clone B6 ?1-chain) fusion protein with peptide linker (GGGGS)3 fusion protein with immunoglobulin [103-cysteine,174-cysteine] anti-(human tumor necrosis factor re
Preferred Name English
Ragistomig
INN  
Official Name English
ragistomig [INN]
Common Name English
fused G1-scFv lambda-heavy heavy chain humanized (1-715) [gamma1 anti-CD274 humanized (1-449) [VH (Homo sapiens IGHV3-48*02 (87.8%) -(IGHD) -IGHJ4*01 (85.7%) L123>T (114), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*03v, G1m3>G1m17
Common Name English
Immunoglobulin G1-scFv_L-kappa dimer, anti-[Homo sapiens CD274 (programmed cell death 1 ligand 1, PDL1,PD-L1, B7 homolog 1, B7H1, B7-H1, PDCD1LG1)] and anti-[Homo sapiens TNFRSF9 (TNF receptor superfamily member 9, 4-1BB, T cell antigen ILA, CD137)], hum
Common Name English
Code System Code Type Description
CAS
2763222-58-6
Created by admin on Wed Apr 02 10:45:24 GMT 2025 , Edited by admin on Wed Apr 02 10:45:24 GMT 2025
PRIMARY
SMS_ID
300000054649
Created by admin on Wed Apr 02 10:45:24 GMT 2025 , Edited by admin on Wed Apr 02 10:45:24 GMT 2025
PRIMARY
NCI_THESAURUS
C203072
Created by admin on Wed Apr 02 10:45:24 GMT 2025 , Edited by admin on Wed Apr 02 10:45:24 GMT 2025
PRIMARY
FDA UNII
6W6Z6G78V3
Created by admin on Wed Apr 02 10:45:24 GMT 2025 , Edited by admin on Wed Apr 02 10:45:24 GMT 2025
PRIMARY
INN
12707
Created by admin on Wed Apr 02 10:45:24 GMT 2025 , Edited by admin on Wed Apr 02 10:45:24 GMT 2025
PRIMARY
From To
4_134 4_194
4_23 4_88
3_134 3_194
3_23 3_88
2_616 2_690
2_567 2_638
2_486 2_553
2_369 2_427
2_263 2_323
2_222 4_214
1_222 3_214
2_146 2_202
2_22 2_96
1_616 1_690
1_567 1_638
1_486 1_553
1_369 1_427
1_263 1_323
1_231 2_231
1_228 2_228
1_146 1_202
1_22 1_96
Related Record Type Details
PROGRAMMED CELL DEATH 1 LIGAND 1
TARGET -> INHIBITOR
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9
TARGET -> AGONIST
T lymphocyte stimulants
Related Record Type Details
Ragistomig
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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