Ragistomig

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:19:35 GMT 2023` Edited by `admin` on `Sat Dec 16 18:19:35 GMT 2023`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	6W6Z6G78V3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ragistomig

Official Name

English

Immunoglobulin G1 [299-alanine], anti-(human programmed death-ligand 1) (human-Mus musculus clone B6 γ1-chain) fusion protein with peptide linker (GGGGS)3 fusion protein with immunoglobulin [103-cysteine,174-cysteine] anti-(human tumor necrosis factor r

Common Name

English

ragistomig [INN]

Common Name

English

fused G1-scFv lambda-heavy heavy chain humanized (1-715) [gamma1 anti-CD274 humanized (1-449) [VH (Homo sapiens IGHV3-48*02 (87.8%) -(IGHD) -IGHJ4*01 (85.7%) L123>T (114), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*03v, G1m3>G1m17

Common Name

English

Immunoglobulin G1-scFv_L-kappa dimer, anti-[Homo sapiens CD274 (programmed cell death 1 ligand 1, PDL1,PD-L1, B7 homolog 1, B7H1, B7-H1, PDCD1LG1)] and anti-[Homo sapiens TNFRSF9 (TNF receptor superfamily member 9, 4-1BB, T cell antigen ILA, CD137)], hum

Common Name

English

Code System Code Type Description

CAS

2763222-58-6

Created by admin on Sat Dec 16 18:19:36 GMT 2023 , Edited by admin on Sat Dec 16 18:19:36 GMT 2023

PRIMARY

FDA UNII

6W6Z6G78V3

Created by admin on Sat Dec 16 18:19:36 GMT 2023 , Edited by admin on Sat Dec 16 18:19:36 GMT 2023

PRIMARY

INN

12707

Created by admin on Sat Dec 16 18:19:36 GMT 2023 , Edited by admin on Sat Dec 16 18:19:36 GMT 2023

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_616	2_690
2_567	2_638
2_486	2_553
2_369	2_427
2_263	2_323
2_222	4_214
1_222	3_214
2_146	2_202
2_22	2_96
1_616	1_690
1_567	1_638
1_486	1_553
1_369	1_427
1_263	1_323
1_231	2_231
1_228	2_228
1_146	1_202
1_22	1_96

Related Record Type Details


					L4766ELH5T

PROGRAMMED CELL DEATH 1 LIGAND 1

TARGET -> INHIBITOR

Amount:


					7VWM3OLK0G

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9

TARGET -> AGONIST

Comments:

T lymphocyte stimulants

Amount:

Related Record Type Details


					6W6Z6G78V3

Ragistomig

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL