MYXOTHIAZOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H33N3O3S2
Molecular Weight	487.678
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	4
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CO[C@@H](\C=C\C1=CSC(=N1)C2=CSC(=N2)[C@@H](C)\C=C\C=C\C(C)C)[C@@H](C)C(\OC)=C/C(N)=O

InChI

InChIKey=XKTFQMCPGMTBMD-FYHMSGCOSA-N

InChI=1S/C25H33N3O3S2/c1-16(2)9-7-8-10-17(3)24-28-20(15-33-24)25-27-19(14-32-25)11-12-21(30-5)18(4)22(31-6)13-23(26)29/h7-18,21H,1-6H3,(H2,26,29)/b9-7+,10-8+,12-11+,22-13+/t17-,18+,21-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C25H33N3O3S2
Molecular Weight	487.678
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	4
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Target ID: cytochrome bc1 oxidoreductase Sources: https://www.ncbi.nlm.nih.gov/pubmed/2753821	Inhibitor 8146

PubMed

Title	Date	PubMed
Myxothiazol, a new inhibitor of the cytochrome b-c1 segment of th respiratory chain.	1981 Dec 14	6274398
Myxothiazol: a reversible blocker of the cell cycle.	1989 Jul	2753821
A mouse model of mitochondrial complex III dysfunction induced by myxothiazol.	2014 Apr 18	24661880

Substance Class	Chemical Created by `admin` on `Sat Dec 17 22:38:41 UTC 2022` Edited by `admin` on `Sat Dec 17 22:38:41 UTC 2022`
Record UNII	6VY98BQ7NB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MYXOTHIAZOL

Common Name

English

(2E,4R,5S,6E)-7-(2'-((1S,2E,4E)-1,6-DIMETHYL-2,4-HEPTADIEN-1-YL)(2,4'-BITHIAZOL)-4-YL)-3,5-DIMETHOXY-4-METHYL-2,6-HEPTADIENAMIDE

Systematic Name

English

MYXOTHIAZOLE A

Common Name

English

2,6-HEPTADIENAMIDE, 7-(2'-((1S,2E,4E)-1,6-DIMETHYL-2,4-HEPTADIENYL)(2,4'-BITHIAZOL)-4-YL)-3,5-DIMETHOXY-4-METHYL-, (2E,4R,5S,6E)-

Systematic Name

English

(+)-MYXOTHIAZOL A

Common Name

English

2,6-HEPTADIENAMIDE, 7-(2'-((1S,2E,4E)-1,6-DIMETHYL-2,4-HEPTADIEN-1-YL)(2,4'-BITHIAZOL)-4-YL)-3,5-DIMETHOXY-4-METHYL-, (2E,4R,5S,6E)-

Systematic Name

English

MYXOTHIAZOL A

Common Name

English

2,6-HEPTADIENAMIDE, 7-(2'-(1,6-DIMETHYL-2,4-HEPTADIENYL)(2,4'-BITHIAZOL)-4-YL)-3,5-DIMETHOXY-4-METHYL-, (4R-(2E,4R*,5S*,6E,7(1S*,2E,4E)))-

Systematic Name

English

Code System Code Type Description

CAS

76706-55-3