1-Tetralone

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H10O
Molecular Weight	146.1858
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1CCCC2=C1C=CC=C2

InChI

InChIKey=XHLHPRDBBAGVEG-UHFFFAOYSA-N

InChI=1S/C10H10O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6H,3,5,7H2

HIDE SMILES / InChI

Molecular Formula	C10H10O
Molecular Weight	146.1858
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
2-Amino-4-(2-fluoro-phen-yl)-5,6-dihydro-benzo[h]quinoline-3-carbonitrile.	2010-12-11	21522805
Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase.	2010-11-30	21152397
2,4-Dinitro-1-naphthol.	2010-11-06	21589407
Secondary metabolites from the red mould rice of Monascus purpureus BCRC 38113.	2010-11	19459082
4-tert-Butyl-4'-(4-meth-oxy-phen-yl)-3'-(4-methyl-phen-yl)-1,2,3,4-tetra-hydro-spiro-[naphthalene-2,5'(4'H)-1,2-oxazol]-1-one.	2010-10-31	21589194
Juglanone, a novel α-tetralonyl derivative with potent antioxidant activity from Juglans mandshurica.	2010-10	20571925
Protoplast mutation and genome shuffling induce the endophytic fungus Tubercularia sp. TF5 to produce new compounds.	2010-10	20232067
Terpenes from marine-derived fungi.	2010-08-13	20948911
Properties and evolution of an alcohol dehydrogenase from the Crenarchaeota Pyrobaculum aerophilum.	2010-08-01	20406673
1-(2,4-Dinitro-phen-yl)-2-(1,2,3,4-tetra-hydro-naphthalen-1-yl-idene)hydrazine.	2010-07-24	21588393
3-(7,8,13,14-Tetra-hydrodi-benzo-[a,i]phen-an-thridin-5-yl)benzene-1,2-diol.	2010-06-23	21587969
The first cyclic phenolic acid glycoside dimer and new alpha-tetralone and triterpenoid glucosides from Gentiana loureirii.	2010-04	20410644
Synthesis and determination of acute and chronic pain activities of 1-[1-(3-methylphenyl) (tetralyl)]piperidine as a new derivative of phencyclidine via tail immersion and formalin tests.	2010	20184224
Some fluorescence properties of dimethylaminochalcone and its novel cyclic analogues.	2009-12	19854674
rac-2-Iodo-3,4-dihydro-naphthalen-1(2H)-one.	2009-11-21	21578887
Selective oxidation of tetralin over a chromium terephthalate metal organic framework, MIL-101.	2009-07-14	19662247
Facile and efficient enantioselective Strecker reaction of ketimines by chiral sodium phosphate.	2009-06-08	19418513
4-(4-Fluoro-phen-yl)-2-oxo-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbonitrile.	2009-05-20	21583205
In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.	2008-12-25	19049427
Two new isomeric alpha-tetralones from Pyrola calliantha.	2008-12	18991208
Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an alpha-tetralone derivative in the green walnut husks (Juglans regia L.).	2008-11-04	18771874
(1'S)-4-(3,4-Dichlorophenyl)-1'-(3,5-dimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-2-spiro-2'-pyrrolizidine-3'-spiro-3''-indoline-1,2''-dione.	2008-09-17	21201161
Simultaneous determination of three diarylheptanoids and an alpha-tetralone derivative in the green walnut husks (Juglans regia L.) by high-performance liquid chromatography with photodiode array detector.	2008-05-09	18343385
4'-Methyl-3-(4-nitro-phen-yl)-4-phenyl-4,5,1',2',3',4'-hexa-hydro-spiro-[isoxazole-5,2'-naphthalen]-1'-one.	2008-01-23	21201529
Enantioselective alpha-arylation of ketones with aryl triflates catalyzed by difluorphos complexes of palladium and nickel.	2008-01-09	18076166
Construction of a chiral central nervous system (CNS)-active aminotetralin drug compound based on a synthesis strategy using multitasking properties of (S)-1-phenylethylamine.	2007-12	17668920
Oxidative carbon-carbon bond formation via silyl bis-enol ethers: controlled cross-coupling for the synthesis of quaternary centers.	2007-10-25	17914838
Metabolites from the xylariaceous fungus PSU-A80.	2007-09	17827754
Molecular biology of cantharidin in cancer cells.	2007-07-04	17610718
Studies on the intramolecular cyclizations of bicyclic delta-hydroxynitriles promoted by triflic anhydride.	2007-05-11	17439177
1,1-dioxonaphtho[1,2-b]thiophene-2-methyloxycarbonyl (alpha-Nsmoc) and 3,3-dioxonaphtho[2,1-b]thiophene-2-methyloxycarbonyl (beta-Nsmoc) amino-protecting groups.	2007-03-02	17286441
Solvent-free iodination of organic molecules using the I(2)/urea-H(2)O(2) reagent system.	2007-02-21	17285178
Synthesis of rigid trichostatin A analogs as HDAC inhibitors.	2006-10-15	16904890
Breakdown products on metabolic pathway of degradation of benz[a]anthracene by a ligninolytic fungus.	2006-07	16403417
General synthesis of 8-aryl-2-tetralones.	2006-06-23	16776527
Cytotoxic and new tetralone derivatives from Berchemia floribunda (Wall.) Brongn.	2006-06	17193298
Synthesis and biological activity of tetralone abscisic acid analogues.	2006-04-07	16557330
Studies of the condensation of sulfones with ketones and aldehydes.	2006-01-20	16408963
Bitterness suppression with zinc sulfate and na-cyclamate: a model of combined peripheral and central neural approaches to flavor modification.	2005-11	16132352
Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1(2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry.	2005-06	16119191
Biaryls and heterobiaryls as alpha-glucosidase and protein tyrosine phosphatase inhibitors.	2005-03-01	15713383
Synthesis and biological properties of 2-hydroxy-1-(1-phenyltetralyl)piperidine and some of its intermediates as derivatives of phencyclidine.	2005	16229117
Brønsted acid-promoted cyclizations of siloxyalkynes with arenes and alkenes.	2004-08-25	15315407
A general route to the synthesis of 1,5-methano- and 1,5-ethano- 2,3,4,5-tetrahydro-1H-3-benzazepines.	2004-08-20	15307752
BINAP/1,4-diamine-ruthenium(II) complexes for efficient asymmetric hydrogenation of 1-tetralones and analogues.	2004-08-05	15281743
The influence of sodium salts on binary mixtures of bitter-tasting compounds.	2004-06	15201210
New alpha-tetralonyl glucosides from the fruit of Juglans mandshurica.	2004-05	15133209
An efficient parallel synthesis of capsazepine and capsazepine analogs.	2004-03	15032662
Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes.	2004-01-27	14730968
Tetralin as a substrate for camphor (cytochrome P450) 5-monooxygenase.	1996-08-15	8806731

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:56:35 GMT 2025` Edited by `admin` on `Mon Mar 31 19:56:35 GMT 2025`
Record UNII	6VT52A15HY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-Tetralone

Systematic Name

English

PHENYLBUTYRATE RELATED COMPOUND B

Preferred Name

English

TETRALONE

Systematic Name

English

1(2H)-NAPHTHALENONE, 3,4-DIHYDRO-

Systematic Name

English

.ALPHA.-TETRALONE

Common Name

English

3,4-DIHYDRONAPHTHALENONE

Systematic Name

English

PHENYLBUTYRATE RELATED COMPOUND B [USP-RS]

Common Name

English

NSC-5171

Code

English

Code System Code Type Description

RS_ITEM_NUM

1614556