1-TETRALONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H10O
Molecular Weight	146.1858
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1CCCC2=C1C=CC=C2

InChI

InChIKey=XHLHPRDBBAGVEG-UHFFFAOYSA-N

InChI=1S/C10H10O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6H,3,5,7H2

HIDE SMILES / InChI

Molecular Formula	C10H10O
Molecular Weight	146.1858
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Tetralin as a substrate for camphor (cytochrome P450) 5-monooxygenase.	1996 Aug 15	8806731
A general route to the synthesis of 1,5-methano- and 1,5-ethano- 2,3,4,5-tetrahydro-1H-3-benzazepines.	2004 Aug 20	15307752
Brønsted acid-promoted cyclizations of siloxyalkynes with arenes and alkenes.	2004 Aug 25	15315407
BINAP/1,4-diamine-ruthenium(II) complexes for efficient asymmetric hydrogenation of 1-tetralones and analogues.	2004 Aug 5	15281743
Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes.	2004 Jan 27	14730968
The influence of sodium salts on binary mixtures of bitter-tasting compounds.	2004 Jun	15201210
An efficient parallel synthesis of capsazepine and capsazepine analogs.	2004 Mar	15032662
New alpha-tetralonyl glucosides from the fruit of Juglans mandshurica.	2004 May	15133209
Synthesis and biological properties of 2-hydroxy-1-(1-phenyltetralyl)piperidine and some of its intermediates as derivatives of phencyclidine.	2005	16229117
Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1(2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry.	2005 Jun	16119191
Biaryls and heterobiaryls as alpha-glucosidase and protein tyrosine phosphatase inhibitors.	2005 Mar 1	15713383
Bitterness suppression with zinc sulfate and na-cyclamate: a model of combined peripheral and central neural approaches to flavor modification.	2005 Nov	16132352
Synthesis and biological activity of tetralone abscisic acid analogues.	2006 Apr 7	16557330
Studies of the condensation of sulfones with ketones and aldehydes.	2006 Jan 20	16408963
Breakdown products on metabolic pathway of degradation of benz[a]anthracene by a ligninolytic fungus.	2006 Jul	16403417
Cytotoxic and new tetralone derivatives from Berchemia floribunda (Wall.) Brongn.	2006 Jun	17193298
General synthesis of 8-aryl-2-tetralones.	2006 Jun 23	16776527
Synthesis of rigid trichostatin A analogs as HDAC inhibitors.	2006 Oct 15	16904890
Construction of a chiral central nervous system (CNS)-active aminotetralin drug compound based on a synthesis strategy using multitasking properties of (S)-1-phenylethylamine.	2007 Dec	17668920
Solvent-free iodination of organic molecules using the I(2)/urea-H(2)O(2) reagent system.	2007 Feb 21	17285178
Molecular biology of cantharidin in cancer cells.	2007 Jul 4	17610718
1,1-dioxonaphtho[1,2-b]thiophene-2-methyloxycarbonyl (alpha-Nsmoc) and 3,3-dioxonaphtho[2,1-b]thiophene-2-methyloxycarbonyl (beta-Nsmoc) amino-protecting groups.	2007 Mar 2	17286441
Studies on the intramolecular cyclizations of bicyclic delta-hydroxynitriles promoted by triflic anhydride.	2007 May 11	17439177
Oxidative carbon-carbon bond formation via silyl bis-enol ethers: controlled cross-coupling for the synthesis of quaternary centers.	2007 Oct 25	17914838
Metabolites from the xylariaceous fungus PSU-A80.	2007 Sep	17827754
Two new isomeric alpha-tetralones from Pyrola calliantha.	2008 Dec	18991208
In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.	2008 Dec 25	19049427
4'-Methyl-3-(4-nitro-phen-yl)-4-phenyl-4,5,1',2',3',4'-hexa-hydro-spiro-[isoxazole-5,2'-naphthalen]-1'-one.	2008 Jan 23	21201529
Enantioselective alpha-arylation of ketones with aryl triflates catalyzed by difluorphos complexes of palladium and nickel.	2008 Jan 9	18076166
Simultaneous determination of three diarylheptanoids and an alpha-tetralone derivative in the green walnut husks (Juglans regia L.) by high-performance liquid chromatography with photodiode array detector.	2008 May 9	18343385
Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an alpha-tetralone derivative in the green walnut husks (Juglans regia L.).	2008 Nov 4	18771874
(1'S)-4-(3,4-Dichlorophenyl)-1'-(3,5-dimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-2-spiro-2'-pyrrolizidine-3'-spiro-3''-indoline-1,2''-dione.	2008 Sep 17	21201161
Some fluorescence properties of dimethylaminochalcone and its novel cyclic analogues.	2009 Dec	19854674
Selective oxidation of tetralin over a chromium terephthalate metal organic framework, MIL-101.	2009 Jul 14	19662247
Facile and efficient enantioselective Strecker reaction of ketimines by chiral sodium phosphate.	2009 Jun 8	19418513
4-(4-Fluoro-phen-yl)-2-oxo-1,2,5,6-tetra-hydro-benzo[h]quinoline-3-carbonitrile.	2009 May 20	21583205
rac-2-Iodo-3,4-dihydro-naphthalen-1(2H)-one.	2009 Nov 21	21578887
Synthesis and determination of acute and chronic pain activities of 1-[1-(3-methylphenyl) (tetralyl)]piperidine as a new derivative of phencyclidine via tail immersion and formalin tests.	2010	20184224
The first cyclic phenolic acid glycoside dimer and new alpha-tetralone and triterpenoid glucosides from Gentiana loureirii.	2010 Apr	20410644
Properties and evolution of an alcohol dehydrogenase from the Crenarchaeota Pyrobaculum aerophilum.	2010 Aug 1	20406673
Terpenes from marine-derived fungi.	2010 Aug 13	20948911
2-Amino-4-(2-fluoro-phen-yl)-5,6-dihydro-benzo[h]quinoline-3-carbonitrile.	2010 Dec 11	21522805
1-(2,4-Dinitro-phen-yl)-2-(1,2,3,4-tetra-hydro-naphthalen-1-yl-idene)hydrazine.	2010 Jul 24	21588393
3-(7,8,13,14-Tetra-hydrodi-benzo-[a,i]phen-an-thridin-5-yl)benzene-1,2-diol.	2010 Jun 23	21587969
Secondary metabolites from the red mould rice of Monascus purpureus BCRC 38113.	2010 Nov	19459082
Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase.	2010 Nov 30	21152397
2,4-Dinitro-1-naphthol.	2010 Nov 6	21589407
Juglanone, a novel α-tetralonyl derivative with potent antioxidant activity from Juglans mandshurica.	2010 Oct	20571925
Protoplast mutation and genome shuffling induce the endophytic fungus Tubercularia sp. TF5 to produce new compounds.	2010 Oct	20232067
4-tert-Butyl-4'-(4-meth-oxy-phen-yl)-3'-(4-methyl-phen-yl)-1,2,3,4-tetra-hydro-spiro-[naphthalene-2,5'(4'H)-1,2-oxazol]-1-one.	2010 Oct 31	21589194

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:46:35 GMT 2023` Edited by `admin` on `Fri Dec 15 19:46:35 GMT 2023`
Record UNII	6VT52A15HY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-TETRALONE

Systematic Name

English

TETRALONE

Systematic Name

English

1(2H)-NAPHTHALENONE, 3,4-DIHYDRO-

Systematic Name

English

.ALPHA.-TETRALONE

Common Name

English

3,4-DIHYDRONAPHTHALENONE

Systematic Name

English

PHENYLBUTYRATE RELATED COMPOUND B [USP-RS]

Common Name

English

NSC-5171

Code

English

PHENYLBUTYRATE RELATED COMPOUND B

Common Name

English

Code System Code Type Description

RS_ITEM_NUM

1614556