6-METHYLMERCAPTOPURINE

CSC1=C2NC=NC2=NC=N1

InChIKey=UIJIQXGRFSPYQW-UHFFFAOYSA-N

InChI=1S/C6H6N4S/c1-11-6-4-5(8-2-7-4)9-3-10-6/h2-3H,1H3,(H,7,8,9,10)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells.	2001 Aug 1	11479220
Utility of measuring 6-methylmercaptopurine and 6-thioguanine nucleotide levels in managing inflammatory bowel disease patients treated with 6-mercaptopurine in a clinical practice setting.	2003 May-Jun	12702978
Therapeutic drug monitoring of thiopurine drugs in patients with inflammatory bowel disease or autoimmune hepatitis.	2004 Nov	15618853
Prediction of genotoxicity of chemical compounds by statistical learning methods.	2005 Jun	15962942
Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis.	2005 Jun	15934057
Initial clinical experience with allopurinol-thiopurine combination therapy in pediatric inflammatory bowel disease.	2008 Dec	18521913
Limited stability of thiopurine metabolites in blood samples: relevant in research and clinical practise.	2010 Jun 1	20399153

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:05:54 UTC 2023` Edited by `admin` on `Fri Dec 15 17:05:54 UTC 2023`
Record UNII	6V404DV25O
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

6-METHYLMERCAPTOPURINE

Systematic Name

English

NSC-20105

Code

English

METHYLMERCAPTOPURINE, 6-

Systematic Name

English

6-methylmercaptopurine [WHO-DD]

Common Name

English

6-(METHYLTHIO)PURINE

Systematic Name

English

Code System Code Type Description

PUBCHEM

5778