Ispectamab Tazide

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:44:57 GMT 2025` Edited by `admin` on `Wed Apr 02 00:44:57 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	6T0D8LA4M5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SP-8893

Preferred Name

English

Ispectamab Tazide

Official Name

English

ispectamab tazide [INN]

Common Name

English

Immunoglobulin G1 [186,410-bis[4-(azidomethyl)-L-phenylalanine]], anti-(human tumor necrosis factor receptor superfamily protein TNFRSF17) (human-Mus musculus monoclonal SP8893 ?1-chain), disulfide with human-Mus musculus monoclonal SP8893 ?-chain, dimer

Common Name

English

Code System Code Type Description

FDA UNII

6T0D8LA4M5

Created by admin on Wed Apr 02 00:44:57 GMT 2025 , Edited by admin on Wed Apr 02 00:44:57 GMT 2025

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SMS_ID

300000046866

Created by admin on Wed Apr 02 00:44:57 GMT 2025 , Edited by admin on Wed Apr 02 00:44:57 GMT 2025

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INN

12139

Created by admin on Wed Apr 02 00:44:57 GMT 2025 , Edited by admin on Wed Apr 02 00:44:57 GMT 2025

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CAS

2585651-78-9

Created by admin on Wed Apr 02 00:44:57 GMT 2025 , Edited by admin on Wed Apr 02 00:44:57 GMT 2025

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NCI_THESAURUS

C190324

Created by admin on Wed Apr 02 00:44:57 GMT 2025 , Edited by admin on Wed Apr 02 00:44:57 GMT 2025

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From	To
1_23	1_97
2_23	2_97
2_150	2_206
2_226	4_215
2_267	2_327
1_150	1_206
2_373	2_431
3_24	3_89
3_135	3_195
4_24	4_89
4_135	4_195
1_226	3_215
1_232	2_232
1_235	2_235
1_267	1_327
1_373	1_431

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_186] [1_410] [2_186] [2_410]	SITE_SPECIFIC			4-AZIDOMETHYL-L-PHENYLALANINE	Y93EFN1C36

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL