Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C23H16O6.2C18H22ClNO |
| Molecular Weight | 996.022 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=C(Cl)C=C2.CN(C)CCOC(C)(C3=CC=CC=C3)C4=CC=C(Cl)C=C4.OC(=O)C5=CC6=CC=CC=C6C(CC7=C(O)C(=CC8=CC=CC=C78)C(O)=O)=C5O
InChI
InChIKey=PGJUOFIHEKUNFO-UHFFFAOYSA-N
InChI=1S/C23H16O6.2C18H22ClNO/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;2*1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2*4-12H,13-14H2,1-3H3
| Molecular Formula | C23H16O6 |
| Molecular Weight | 388.3695 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C18H22ClNO |
| Molecular Weight | 303.826 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
DescriptionCurator's Comment: Description was created based on several sources, including
https://www.drugs.com/international/systral.html
http://en.pharmacodia.com/web/drug/1_10746.html
Curator's Comment: Description was created based on several sources, including
https://www.drugs.com/international/systral.html
http://en.pharmacodia.com/web/drug/1_10746.html
Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and was formerly used in the sympathomimetic treatment of parkinsonism. Histamine receptor H1 antagonist. Chlorphenoxamine is used to treat Allergic conditions, it is reported as an ingredient of Systral in Germany, Malta, Portugal, Thailand, Turkey.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| In vitro antibacterial activity of some systemic and topical antihistaminic preparations. | 2009-12-01 |
|
| Spectrophotometric determination of some histamine H1-antagonists drugs in their pharmaceutical preparations. | 2008-01 |
|
| Aspirin-induced unilateral angioedema of the tongue. | 2006-05 |
|
| Simultaneous determination of caffeine, 8-chlorotheophylline, and chlorphenoxamine hydrochloride in ternary mixtures by ratio-spectra zero-crossing first-derivative spectrophotometric and chemometric methods. | 2005-09-13 |
|
| [Significance of chromatographic methods coupled with mass spectrometry for identification of drugs for medico-legal purposes exemplified by chlorphenoxamine]. | 2003-12-13 |
|
| Simultaneous spectrophotometric determination of chlorphenoxamine hydrochloride and caffeine in a pharmaceutical preparation using first derivative of the ratio spectra and chemometric methods. | 2002-05-15 |
|
| [Antimycobacterial antihistaminics]. | 1989-08 |
Patents
| Substance Class |
Chemical
Created
by
admin
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Edited
Mon Mar 31 21:29:29 GMT 2025
by
admin
on
Mon Mar 31 21:29:29 GMT 2025
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| Record UNII |
6RZ7C08DLL
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| Record Status |
Validated (UNII)
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| Record Version |
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139032930
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6RZ7C08DLL
Created by
admin on Mon Mar 31 21:29:29 GMT 2025 , Edited by admin on Mon Mar 31 21:29:29 GMT 2025
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300000048976
Created by
admin on Mon Mar 31 21:29:29 GMT 2025 , Edited by admin on Mon Mar 31 21:29:29 GMT 2025
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