3-HYDROXY-2-(4-METHOXYPHENYL)-2,3-DIHYDRO-1,5-BENZOTHIAZEPIN-4(5H)-ONE, (2S,3S)-

COC1=CC=C(C=C1)[C@@H]2SC3=CC=CC=C3NC(=O)[C@@H]2O

InChIKey=LHBHZALHFIQJGJ-CABCVRRESA-N

InChI=1S/C16H15NO3S/c1-20-11-8-6-10(7-9-11)15-14(18)16(19)17-12-4-2-3-5-13(12)21-15/h2-9,14-15,18H,1H3,(H,17,19)/t14-,15+/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5h)-one, (2S,3S)- is one of diltiazem impurity.

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Analysis of diltiazem and its related substances by HPLC and HPLC/MS.	2005-04-01	15797790

Patents

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:13:25 GMT 2025` Edited by `admin` on `Mon Mar 31 18:13:25 GMT 2025`
Record UNII	6RN4N3305M
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

3-HYDROXY-2-(4-METHOXYPHENYL)-2,3-DIHYDRO-1,5-BENZOTHIAZEPIN-4(5H)-ONE, (2S,3S)-

Systematic Name

English

(2S,3S)-3-HYDROXY-2-(4-METHOXYPHENYL)-2,3-DIHYDRO-1,5-BENZOTHIAZEPIN-4(5H)-ONE

Preferred Name

English

1,5-BENZOTHIAZEPIN-4(5H)-ONE, 2,3-DIHYDRO-3-HYDROXY-2-(4-METHOXYPHENYL)-, (2S-CIS)-

Systematic Name

English

DILTIAZEM HYDROCHLORIDE IMPURITY E [EP IMPURITY]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID6057744