U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8F18
Molecular Weight 438.0569
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PERFLUOROOCTANE

SMILES

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI

InChIKey=YVBBRRALBYAZBM-UHFFFAOYSA-N
InChI=1S/C8F18/c9-1(10,3(13,14)5(17,18)7(21,22)23)2(11,12)4(15,16)6(19,20)8(24,25)26

HIDE SMILES / InChI

Molecular Formula C8F18
Molecular Weight 438.0569
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of perfluorocarbon liquids and silicone oil on human retinal pigment epithelial cells and retinal ganglion cells.
2009-05
Association among serum perfluoroalkyl chemicals, glucose homeostasis, and metabolic syndrome in adolescents and adults.
2009-04
Binding of PFOS to serum albumin and DNA: insight into the molecular toxicity of perfluorochemicals.
2009-02-25
Changes in retinal sensitivity from retained subretinal perfluorocarbon liquid.
2009-02
Environmental hazards and health risk of common liquid perfluoro-n-alkanes, potent greenhouse gases.
2009-02
Contribution to the evaluation of reference values for PFOA and PFOS in plasma of children and adults from Germany.
2009-01
Comparative analysis of state fish consumption advisories targeting sensitive populations.
2008-12
Perfluorooctane sulfonate (PFOS) and other fluorochemicals in fish blood collected near the outfall of wastewater treatment plant (WWTP) in Beijing.
2008-12
Perfluorooctane sulfonate-induced changes in fetal rat liver gene expression.
2008-09-29
Fluorescence lifetime imaging of mixing dynamics in continuous-flow microdroplet reactors.
2008-07-04
Solvation of perfluorooctane and octane in water, methanol, acetonitrile, and aqueous mixtures of methanol and acetonitrile.
2008-07-03
Retained perfluoron postvitreoretinal surgery causing secondary open-angle glaucoma.
2008-06
En bloc perfluorodissection for tractional retinal detachment in proliferative diabetic retinopathy.
2008-06
An epidemic of sticky silicone oil at the Rotterdam Eye Hospital. Patient review and chemical analyses.
2008-06
Solvation of halogens in fluorous phases. Experimental and simulation data for F2, Cl2, and Br2 in several fluorinated liquids.
2008-05-29
Perfluorooctane surfactants in waste waters, the major source of river pollution.
2008-05
Aerobic biotransformation and fate of N-ethyl perfluorooctane sulfonamidoethanol (N-EtFOSE) in activated sludge.
2008-04-15
En bloc perfluorodissection in vitreoretinal surgery: a new surgical technique.
2008-04
Inhibition of the adenine nucleotide translocator by N-acetyl perfluorooctane sulfonamides in vitro.
2008-03-01
Perfluorodecaline residue in the anterior chamber of a patient with an intact crystalline lens: a case report.
2008-01-22
Subretinal perfluorocarbon removal: perfluorocarbon volume estimation and cannula choice.
2008-01
Persistent retinal macrocyst following pars plana vitrectomy for rhegmatogenous retinal detachment.
2007-12
Exposure of an adult population to perfluorinated substances using duplicate diet portions and biomonitoring data.
2007-11-15
Perfluorinated chemicals and fetal growth: a study within the Danish National Birth Cohort.
2007-11
Cord serum concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in relation to weight and size at birth.
2007-11
Perfluoroalkyl acids: a review of monitoring and toxicological findings.
2007-10
Perfluorocarbon-perfused vitrectomy using a transconjunctival 25-gauge system.
2007-09
Perfluorinated compounds in the Pearl River and Yangtze River of China.
2007-08
Removal of residual subfoveal perfluoro-n-octane liquid.
2007-07
Historical trends in human serum levels of perfluorooctanoate and perfluorooctane sulfonate in Shenyang, China.
2007-05
[Deposits of perfluoroctane after prolonged use as a post-operative vitreous substitute].
2007-04
Effect of flux (transmembrane pressure) and membrane properties on fouling and rejection of reverse osmosis and nanofiltration membranes treating perfluorooctane sulfonate containing wastewater.
2007-03-15
Pars plana vitrectomy, laser retinopexy, and aqueous tamponade for pseudophakic rhegmatogenous retinal detachment.
2007-02
Fluorochemical mass flows in a municipal wastewater treatment facility.
2006-12-01
Solubilization of various fluorocarbons in a fluorinated surfactant/water system: relation with the design of porous materials.
2006-11-23
The applicability of biomonitoring data for perfluorooctanesulfonate to the environmental public health continuum.
2006-11
Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys--probing the determinants of long plasma half-lives.
2006-10-03
Esterification prevents induction of the mitochondrial permeability transition by N-acetyl perfluorooctane sulfonamides.
2006-10
Application of YAG laser retinopuncture for perfluorocarbon liquid removal from under retina after vitreoretinal surgery.
2006-10
Long-term tamponade of perfluorocarbon liquid (PCL).
2006-09
Using perfluoro-n-octane as a postoperative tamponade in the management of giant retinal tears.
2006-07-11
Conformational analysis of chiral helical perfluoroalkyl chains by VCD.
2006-05-10
Fluidization of a dipalmitoyl phosphatidylcholine monolayer by fluorocarbon gases: potential use in lung surfactant therapy.
2006-05-01
Atmospheric chemistry of N-methyl perfluorobutane sulfonamidoethanol, C4F9SO2N(CH3)CH2CH2OH: kinetics and mechanism of reaction with OH.
2006-03-15
Vapor pressure determinations of 8-2 fluorortelomer alcohol and 1-H perfluorooctane by capillary gas chromatography Relative retention time versus headspace methods.
2006-03-10
[Perfluoroctane liquid as a short-term vitreous-retinal tamponade in the postoperative period in patients with retinal detachment due to giant tears].
2006-03-06
Phacoemulsification in the vitreous cavity for retained nuclear lens fragments.
2006-02-24
Ocular coherence tomography findings with retained submacular perfluoron.
2006-02-03
Comparative effects of vaporized perfluorohexane and partial liquid ventilation in oleic acid-induced lung injury.
2006-02
Primary pars plana vitrectomy versus scleral buckle surgery for the treatment of pseudophakic retinal detachment: a randomized clinical trial.
2005-12
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:56:37 GMT 2025
Edited
by admin
on Mon Mar 31 18:56:37 GMT 2025
Record UNII
6P60ZBK0QL
Record Status Validated (UNII)
Record Version
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Name Type Language
PERFLUOROOCTANE [MART.]
Preferred Name English
PERFLUOROOCTANE
MART.   WHO-DD  
Systematic Name English
Perfluorooctane [WHO-DD]
Common Name English
Code System Code Type Description
PUBCHEM
9387
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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WIKIPEDIA
PERFLUOROOCTANE
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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FDA UNII
6P60ZBK0QL
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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MESH
C073608
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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EVMPD
SUB33876
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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CAS
307-34-6
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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EPA CompTox
DTXSID0059794
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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ECHA (EC/EINECS)
206-199-2
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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SMS_ID
100000127764
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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CHEBI
38826
Created by admin on Mon Mar 31 18:56:37 GMT 2025 , Edited by admin on Mon Mar 31 18:56:37 GMT 2025
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