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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 16:50:57 GMT 2025
Edited
by admin
on Tue Apr 01 16:50:57 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
6OU487748Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SUBSTANCE-P RECEPTOR
Common Name English
NEUROKININ-1 RECEPTOR
Preferred Name English
TACHYKININ RECEPTOR 1
Common Name English
NK-1 RECEPTOR
Common Name English
TACR1
Common Name English
NK1 RECEPTOR
Common Name English
NK1R
Common Name English
Code System Code Type Description
FDA UNII
6OU487748Q
Created by admin on Tue Apr 01 16:50:57 GMT 2025 , Edited by admin on Tue Apr 01 16:50:57 GMT 2025
PRIMARY
WIKIPEDIA
Tachykinin receptor 1
Created by admin on Tue Apr 01 16:50:57 GMT 2025 , Edited by admin on Tue Apr 01 16:50:57 GMT 2025
PRIMARY
PHAROS
P25103
Created by admin on Tue Apr 01 16:50:57 GMT 2025 , Edited by admin on Tue Apr 01 16:50:57 GMT 2025
PRIMARY
UNIPROT
P25103
Created by admin on Tue Apr 01 16:50:57 GMT 2025 , Edited by admin on Tue Apr 01 16:50:57 GMT 2025
PRIMARY
From To
1_105 1_180
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_14
N 1_18
Related Record Type Details
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ANTAGONIST
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Structure of ORVEPITANT
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Structure of FIGOPITANT
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SELECTIVE
Structure of EZLOPITANT
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Structure of TRADIPITANT
INHIBITOR -> TARGET
Structure of AVE-5883
INHIBITOR -> TARGET
Ki
SUBSTANCE P
AGONIST -> TARGET
Structure of VOFOPITANT C-11
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Structure of NOLPITANTIUM
INHIBITOR -> TARGET
Structure of L-760735F
INHIBITOR -> TARGET
Structure of DAPITANT
INHIBITOR -> TARGET
Structure of VOFOPITANT
INHIBITOR -> TARGET
Structure of SPA-RQ F-18
RADIOLIGAND->TARGET
Structure of R-116031
INHIBITOR -> TARGET
> 200-fold selectivity against NK2 and NK3 receptors
Ki
Structure of CS-003 FREE BASE
INHIBITOR -> TARGET
Structure of FK-888
INHIBITOR -> TARGET
IC50
Structure of DNK-333
INHIBITOR -> TARGET
Structure of CASOPITANT
INHIBITOR -> TARGET
Structure of SLV-317 FREE BASE
INHIBITOR -> TARGET
Structure of BEFETUPITANT
INHIBITOR -> TARGET
Structure of VESTIPITANT
INHIBITOR -> TARGET
Structure of LANEPITANT
INHIBITOR -> TARGET
Structure of NERATINIB
INHIBITOR->OFF-TARGET
INHIBITOR
Percent inhibition of specific binding
Structure of TELMAPITANT
INHIBITOR -> TARGET
Structure of TALNETANT
NON-INHIBITOR->OFF TARGET
Ki
Structure of TA-5538
INHIBITOR -> TARGET
Structure of Burapitant
INHIBITOR -> TARGET
HUMAN IM CELLS
BINDING
Ki
Structure of SERLOPITANT
INHIBITOR -> TARGET
Structure of TAK-480
NON-INHIBITOR->OFF TARGET
IC50
Structure of FE-SPA-RQ F-18
RADIOLIGAND->TARGET
Structure of SCH-720881
INHIBITOR -> TARGET
Structure of IMNOPITANT
INHIBITOR -> TARGET
Structure of NETUPITANT
INHIBITOR -> TARGET
Structure of APREPITANT
INHIBITOR -> TARGET
ANTAGONIST
Structure of MAROPITANT
INHIBITOR -> TARGET
Structure of ELINZANETANT
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL
NIH
NCATS
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