SUBSTANCE-P RECEPTOR

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:43:22 UTC 2023` Edited by `admin` on `Sat Dec 16 11:43:22 UTC 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	6OU487748Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SUBSTANCE-P RECEPTOR

Common Name

English

TACHYKININ RECEPTOR 1

Common Name

English

NK-1 RECEPTOR

Common Name

English

TACR1

Common Name

English

NK1 RECEPTOR

Common Name

English

NK1R

Common Name

English

NEUROKININ-1 RECEPTOR

Common Name

English

Code System Code Type Description

FDA UNII

6OU487748Q

Created by admin on Sat Dec 16 11:43:24 UTC 2023 , Edited by admin on Sat Dec 16 11:43:24 UTC 2023

PRIMARY

WIKIPEDIA

Tachykinin receptor 1

Created by admin on Sat Dec 16 11:43:24 UTC 2023 , Edited by admin on Sat Dec 16 11:43:24 UTC 2023

PRIMARY

PHAROS

P25103

Created by admin on Sat Dec 16 11:43:24 UTC 2023 , Edited by admin on Sat Dec 16 11:43:24 UTC 2023

PRIMARY

UNIPROT

P25103

Created by admin on Sat Dec 16 11:43:24 UTC 2023 , Edited by admin on Sat Dec 16 11:43:24 UTC 2023

PRIMARY

From	To
1_105	1_180

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_14
N	1_18

Related Record Type Details


					NLE429IZUC

ROLAPITANT

INHIBITOR -> TARGET

Interaction Type:

ANTAGONIST

Amount:


					44S7GN2UDJ

DOTA-Arg-Pro-Lys-Pro-Gln-Gln-Phe-2Thi-Gly-Leu-Met(O2)-NH2 Actinium AC-225

RADIOLIGAND->TARGET

Comments:

Used to treat glioma.

Amount:


					IIU6V0W3JD

ORVEPITANT

INHIBITOR -> TARGET

Amount:


					Q2B1Q52A8J

SCH-900978

INHIBITOR -> TARGET

Amount:


					23X73B9O6Q

FIGOPITANT

INHIBITOR -> TARGET

Amount:


					R7OYP6N58F

CP-122721

INHIBITOR -> TARGET

Interaction Type:

SELECTIVE

Amount:


					3L098A8MPY

EZLOPITANT

INHIBITOR -> TARGET

Qualification:

Ki

Amount:


					YA427LW2Y2

AVE-5883

INHIBITOR -> TARGET

Qualification:

Ki

Amount:


					675VGV5J1D

SUBSTANCE P

AGONIST -> TARGET

Amount:


					XWN7G45JKF

VOFOPITANT C-11

RADIOLIGAND->TARGET

Amount:


					NR72W2V70N

NOLPITANTIUM

INHIBITOR -> TARGET

Amount:


					4I4P4I2E8P

L-760735F

INHIBITOR -> TARGET

Amount:


					NRD5XF638P

DAPITANT

INHIBITOR -> TARGET

Amount:


					K08BK043YS

VOFOPITANT

INHIBITOR -> TARGET

Amount:


					4YL3GT1EV9

SPA-RQ F-18

RADIOLIGAND->TARGET

Amount:


					VGDEDKUKP2

CS-003 FREE BASE

INHIBITOR -> TARGET

Amount:


					G9BL4978MZ

DNK-333

INHIBITOR -> TARGET

Amount:


					3B03KPM27L

CASOPITANT

INHIBITOR -> TARGET

Amount:


					EFL393CK3S

SCH-720881

INHIBITOR -> TARGET

Interaction Type:

ANTAGONIST

Qualification:

Ki

Amount:


					RSH7NDI7MI

BEFETUPITANT

INHIBITOR -> TARGET

Amount:


					S052TOI9BI

VESTIPITANT

INHIBITOR -> TARGET

Amount:


					17G8FN2E1F

LANEPITANT

INHIBITOR -> TARGET

Amount:


					JJH94R3PWB

NERATINIB

INHIBITOR->OFF-TARGET

Interaction Type:

INHIBITOR

Qualification:

Percent inhibition of specific binding

Amount:


					HJ5FE4153B

TELMAPITANT

INHIBITOR -> TARGET

Amount:


					WPL66843QN

SLV-317 FREE BASE

INHIBITOR -> TARGET

Interaction Type:

INHIBITOR


					E35SK332MS

BURAPITANT

INHIBITOR -> TARGET

Amount:


					277V92K32B

SERLOPITANT

INHIBITOR -> TARGET

Amount:


					NY0COC51FI

TRADIPITANT

INHIBITOR -> TARGET

Interaction Type:

ANTAGONIST


					D8HE7NY47J

FE-SPA-RQ F-18

RADIOLIGAND->TARGET

Amount:


					F1516R3E77

IMNOPITANT

INHIBITOR -> TARGET

Amount:


					7732P08TIR

NETUPITANT

INHIBITOR -> TARGET

Amount:


					1NF15YR6UY

APREPITANT

INHIBITOR -> TARGET

Interaction Type:

ANTAGONIST

Amount:


					4XE2T9H4DH

MAROPITANT

INHIBITOR -> TARGET

Amount:


					NZW2BOW35N

ELINZANETANT

INHIBITOR -> TARGET

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL