AMADINONE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H25ClO3
Molecular Weight	348.864
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC[C@](O)(C(C)=O)[C@@]1(C)CC[C@]3([H])[C@@]4([H])CCC(=O)C=C4C(Cl)=C[C@@]23[H]

InChI

InChIKey=ANJGIFXUFSBZPX-WLCXVKOPSA-N

InChI=1S/C20H25ClO3/c1-11(22)20(24)8-6-17-15-10-18(21)16-9-12(23)3-4-13(16)14(15)5-7-19(17,20)2/h9-10,13-15,17,24H,3-8H2,1-2H3/t13-,14-,15-,17+,19+,20+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H25ClO3
Molecular Weight	348.864
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5017374 | https://books.google.ru/books?id=7JPsCAAAQBAJ&pg=PA495&redir_esc=y#v=onepage

Amadione is a steroidal progestogenic antiandrogen. Its anti-androgenic properties were confirmed by blockade of androgen-induced increase in seminal acid phosphatase content.

Approval Year

PubMed

Title	Date	PubMed
Seminal acid phosphatase content in the clinical bioassay of androgens and antiandrogens.	1972 Mar-Apr	5017374

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:09:57 GMT 2023` Edited by `admin` on `Sat Dec 16 17:09:57 GMT 2023`
Record UNII	6MB06022N0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMADINONE

Official Name

English

6-CHLORO-17-HYDROXY-19-NORPREGNA-4,6-DIENE-3,20-DIONE

Common Name

English

amadinone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C242