SULFOGAIACOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8O5S
Molecular Weight	204.2
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(=CC=C1O)S(O)(=O)=O

InChI

InChIKey=QDRCGSIKAHSALR-UHFFFAOYSA-N

InChI=1S/C7H8O5S/c1-12-7-4-5(13(9,10)11)2-3-6(7)8/h2-4,8H,1H3,(H,9,10,11)

HIDE SMILES / InChI

Molecular Formula	C7H8O5S
Molecular Weight	204.2
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugs.com/cdi/potassium-guaiacolsulfonate.html

Potassium guaiacolsulfonate also known as sulfoguaiacolum is a salt of GUAIACOLSULFONIC ACID, which is used as an expectorant, to relieve symptoms of cough and mucus in the chest due to respiratory infections, asthma, colds, or hay fever. It works by thinning mucus (phlegm) in the lungs, making it less sticky and easier to cough up. This reduces chest congestion by making coughs more productive.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Respiratory infections 12 Sources: https://www.drugs.com/cdi/potassium-guaiacolsulfonate.html	Palliative	Not Provided 504	Unknown Approved Use Unknown
Asthma 241 Sources: https://www.drugs.com/cdi/potassium-guaiacolsulfonate.html	Palliative	Not Provided 504	Unknown Approved Use Unknown
Common cold 58 Sources: https://www.drugs.com/cdi/potassium-guaiacolsulfonate.html	Palliative	Not Provided 504	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Determination of potassium guaiacolsulfonate by ion-pairing partition chromatography.	1975 Mar	237875
Applications of paired ion high-pressure liquid chromatography: quantitative determination of potassium guaiacolsulfonate and other ingredients in cough syrups.	1979 Jan	758448
Physicochemical properties and method for determination of potassium guaiacolsulfonate.	1987 Jul-Aug	3624174
A New UPLC Approach for the Simultaneous Quantitative Estimation of Four Compounds in a Cough Syrup Formulation.	2016 Jan	26202585

Patents

Sample Use Guides

In Vivo Use Guide

Take potassium guaiacolsulfonate by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. Take potassium guaiacolsulfonate with a full glass of water (8 oz/240 mL). Drink plenty of water while taking potassium guaiacolsulfonate. Do not take 2 doses at once.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:31:39 UTC 2023` Edited by `admin` on `Sat Dec 16 16:31:39 UTC 2023`
Record UNII	6L00O0WHZR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SULFOGAIACOL

Official Name

English

4-HYDROXY-3-METHOXYBENZENESULFONIC ACID

Systematic Name

English

BENZENESULFONIC ACID, 4-HYDROXY-3-METHOXY-

Common Name

English

Sulfogaiacol [WHO-DD]

Common Name

English

4-GUAIACOLSULFONIC ACID

Systematic Name

English

sulfogaiacol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29767