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VOLANESORSEN SODIUM
6JON30SLDT
Investigational
General
Record Details
Names
7
Classification
4
Identifiers
7
Subunits
1
Sugars
2
Linkages
1
Relationships
1
Active Moiety
1
Modifications
1
VOLANESORSEN SODIUM
6JON30SLDT
Investigational
General
Approval Year
Unknown
139,594
Record Details
Substance Class
Nucleic Acid
Nucleic Acid Type
OLIGONUCLEOTIDE
Nucleic Acid Subtype
Record UNII
6JON30SLDT
Record Status
Validated (UNII)
Record Version
16
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11
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9
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4
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2
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Names
7
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5
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entries
Name
Type
Language
Name
Type
Language
VOLANESORSEN SODIUM
Official Name
English
ISIS-304801 SODIUM
Code
English
ISIS 304801 SODIUM SALT
Code
English
Volanesorsen sodium [WHO-DD]
Common Name
English
ISIS-304801 SODIUM SALT
Code
English
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Classification
4
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Agent Affecting Digestive System or Metabolism
Pharmacologic Substance
[C1909]
Agent Affecting Digestive System or Metabolism
[C78276]
Antilipidemic Agent
NCI_THESAURUS
C29703
Designated
ORPHAN DRUG
Designated
treatment of familial chylomicronemia syndrome
FDA ORPHAN DRUG
480815
Gene Therapy Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Gene Therapy Agent
[C1962]
Antisense Oligonucleotides
NCI_THESAURUS
C1291
Positive
EU ORPHAN DRUG
Positive
Treatment of familial partial lipodystrophy
EU-Orphan Drug
EU/3/16/1711
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Identifiers
7
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Code System
Code
Type
Description
Code System
Code
Type
Description
MERCK INDEX
m12145
PRIMARY
NCI_THESAURUS
C152905
PRIMARY
CAS
1573402-50-2
PRIMARY
PUBCHEM
121494122
PRIMARY
USAN
BC-134
PRIMARY
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Subunits
1
Sugars
2
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Sugar
Site Range
Site Count
Sugar
Site Range
Site Count
2'-O-Methoxyethyl ribose
1_1-1_5;1_16-1_20
10 / 20
Deoxyribose (DNA)
1_6-1_15
10 / 20
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Linkages
1
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Linkage
Site Range
Site Count
Linkage
Site Range
Site Count
Sodium Phosporothioate
1_2-1_20
19 / 19
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Relationships
1
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Related Record
Type
Details
Related Record
Type
Details
2O4BE0K238
VOLANESORSEN
PARENT -> SALT/SOLVATE
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Active Moiety
1
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Related Record
Type
Details
Related Record
Type
Details
2O4BE0K238
VOLANESORSEN
ACTIVE MOIETY
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Modifications
1
Structural Modifications
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entries
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
NUCLEOSIDE_SUBSTITUTION
[1_6] [1_11] [1_12] [1_15]
SITE_SPECIFIC
5-METHYLDEOXYCYTIDINE
B200GV71QM
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