.ALPHA.-PYRROLIDINOVALEROTHIOPHENONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H19NOS
Molecular Weight	237.361
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of .ALPHA.-PYRROLIDINOVALEROTHIOPHENONE

Structure Search

SMILES

CCCC(N1CCCC1)C(=O)C2=CC=CS2

InChI

InChIKey=OOSRPGUQJAKBLV-UHFFFAOYSA-N

InChI=1S/C13H19NOS/c1-2-6-11(14-8-3-4-9-14)13(15)12-7-5-10-16-12/h5,7,10-11H,2-4,6,8-9H2,1H3

HIDE SMILES / InChI

Molecular Formula	C13H19NOS
Molecular Weight	237.361
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine transporter 180 Target ID: CHEMBL238 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8297		0.3428 µM [IC50]
Serotonin transporter 178 Target ID: CHEMBL228 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8297		242.0 µM [IC50]
Norepinephrine transporter 191 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8297		0.175 µM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:51:43 UTC 2023` Edited by `admin` on `Sat Dec 16 10:51:43 UTC 2023`
Record UNII	6JA2K09914
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

.ALPHA.-PYRROLIDINOVALEROTHIOPHENONE

Systematic Name

English

.ALPHA.-PVT

Common Name

English

1-PENTANONE, 2-(1-PYRROLIDINYL)-1-(2-THIENYL)-

Systematic Name

English

2-(PYRROLIDIN-1-YL)-1-(THIOPHEN-2-YL)PENTAN-1-ONE

Systematic Name

English

J3.283.187G

Code

English

.ALPHA.-PYRROLIDINOPENTIOTHIOPHENONE

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-.ALPHA.-PYRROLIDINOVALEROTHIOPHENONE

Created by admin on Sat Dec 16 10:51:43 UTC 2023 , Edited by admin on Sat Dec 16 10:51:43 UTC 2023

Code System Code Type Description

WIKIPEDIA

ALPHA-PYRROLIDINOPENTIOTHIOPHENONE

Created by admin on Sat Dec 16 10:51:43 UTC 2023 , Edited by admin on Sat Dec 16 10:51:43 UTC 2023

PRIMARY

α-Pyrrolidinopentiothiophenone (also known as α-PVT) is a synthetic stimulant of the cathinone class that has been sold online as a designer drug. It is a analogue of α-PVP where the phenyl ring has been replaced by thiophene. α-PVT was first identified in Japan in 2013. Its metabolism has been described in literature. Sweden's public health agency suggested classifying α-PVT as hazardous substance on November 10, 2014. As of October 2015 α-PVT is a controlled substance in China. α-PVT is illegal in Switzerland as of December 2015.

PUBCHEM

71721462

Created by admin on Sat Dec 16 10:51:43 UTC 2023 , Edited by admin on Sat Dec 16 10:51:43 UTC 2023

PRIMARY

EPA CompTox

DTXSID90857020

Created by admin on Sat Dec 16 10:51:43 UTC 2023 , Edited by admin on Sat Dec 16 10:51:43 UTC 2023

PRIMARY

MANUFACTURER PRODUCT INFORMATION

.ALPHA.-PYRROLIDINOVALEROTHIOPHENONE

Created by admin on Sat Dec 16 10:51:43 UTC 2023 , Edited by admin on Sat Dec 16 10:51:43 UTC 2023

PRIMARY

CAS

1400742-66-6

Created by admin on Sat Dec 16 10:51:43 UTC 2023 , Edited by admin on Sat Dec 16 10:51:43 UTC 2023

PRIMARY

FDA UNII

6JA2K09914

Created by admin on Sat Dec 16 10:51:43 UTC 2023 , Edited by admin on Sat Dec 16 10:51:43 UTC 2023

PRIMARY

Related Record Type Details


					6JA2K09914

.ALPHA.-PYRROLIDINOVALEROTHIOPHENONE

ACTIVE MOIETY