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Details

Stereochemistry ABSOLUTE
Molecular Formula C17H13F3N2O
Molecular Weight 318.2931
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AZD-0947

SMILES

FC(F)(F)C1=C[C@@H](C2=CC=CC(=C2)C#N)C3=C(CCCC3=O)N1

InChI

InChIKey=RUVMMEREJMHLOS-LBPRGKRZSA-N
InChI=1S/C17H13F3N2O/c18-17(19,20)15-8-12(11-4-1-3-10(7-11)9-21)16-13(22-15)5-2-6-14(16)23/h1,3-4,7-8,12,22H,2,5-6H2/t12-/m0/s1

HIDE SMILES / InChI

Molecular Formula C17H13F3N2O
Molecular Weight 318.2931
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 18:45:51 GMT 2023
Edited
by admin
on Sat Dec 16 18:45:51 GMT 2023
Record UNII
6J3ZRL30TZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AZD-0947
Common Name English
ZD-0947
Code English
ZD0947
Code English
BENZONITRILE, 3-(1,4,5,6,7,8-HEXAHYDRO-5-OXO-2-(TRIFLUOROMETHYL)-4-QUINOLINYL)-, (S)-
Systematic Name English
ZD 0947
Code English
Code System Code Type Description
CAS
172649-40-0
Created by admin on Sat Dec 16 18:45:51 GMT 2023 , Edited by admin on Sat Dec 16 18:45:51 GMT 2023
PRIMARY
MANUFACTURER PRODUCT INFORMATION
AZD-0947
Created by admin on Sat Dec 16 18:45:51 GMT 2023 , Edited by admin on Sat Dec 16 18:45:51 GMT 2023
PRIMARY <b>AZD 0947</b> is a potassium channel opener that was under development with AstraZeneca (formed by the merger of Astra and Zeneca in April 1999). It was in??...
FDA UNII
6J3ZRL30TZ
Created by admin on Sat Dec 16 18:45:51 GMT 2023 , Edited by admin on Sat Dec 16 18:45:51 GMT 2023
PRIMARY
PUBCHEM
9818432
Created by admin on Sat Dec 16 18:45:51 GMT 2023 , Edited by admin on Sat Dec 16 18:45:51 GMT 2023
PRIMARY
EPA CompTox
DTXSID20431296
Created by admin on Sat Dec 16 18:45:51 GMT 2023 , Edited by admin on Sat Dec 16 18:45:51 GMT 2023
PRIMARY
MANUFACTURER PRODUCT INFORMATION
ZD-0947
Created by admin on Sat Dec 16 18:45:51 GMT 2023 , Edited by admin on Sat Dec 16 18:45:51 GMT 2023
PRIMARY AZD0947 is a K+ channel opener, which was under investigation by AstraZeneca for the treatment of overactive bladder. As of March 2003, the drug was in phase II trials; however, as of October 2004, it no longer appeared on the company?s development pipeline.
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