GEDIVUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 13:26:53 GMT 2023` Edited by `admin` on `Sat Dec 16 13:26:53 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	6IRE1TI49I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GEDIVUMAB

Official Name

English

gedivumab [INN]

Common Name

English

RG7745

Code

English

MHAA4549A

Code

English

IMMUNOGLOBULIN G1, ANTI-(INFLUENZA A VIRUS VIRAL HEMAGGLUTININ) (HUMAN MONOCLONAL MHAA4549A HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MHAA4549A LIGHT CHAIN, DIMER

Systematic Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-( INFLUENZA A VIRUS HEMAGGLUTININ)HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-455) (HOMO SAPIENS VH (IGHV3-30*01 (90%) (IGHD)-IGHJ4*01 (87%)) (8.8.18) (1-125) -HOMO SAPIENS IGHG1*03 (CH1(R97>K(222)) (126-455)) (2

Systematic Name

English

GEDIVUMAB [USAN]

Common Name

English

RO6876802

Code

English

Code System Code Type Description

NCI_THESAURUS

C166943

Created by admin on Sat Dec 16 13:26:54 GMT 2023 , Edited by admin on Sat Dec 16 13:26:54 GMT 2023

PRIMARY

USAN

FG-73

Created by admin on Sat Dec 16 13:26:54 GMT 2023 , Edited by admin on Sat Dec 16 13:26:54 GMT 2023

PRIMARY

INN

10459

Created by admin on Sat Dec 16 13:26:54 GMT 2023 , Edited by admin on Sat Dec 16 13:26:54 GMT 2023

PRIMARY

FDA UNII

6IRE1TI49I

Created by admin on Sat Dec 16 13:26:54 GMT 2023 , Edited by admin on Sat Dec 16 13:26:54 GMT 2023

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DRUG BANK

DB15277

Created by admin on Sat Dec 16 13:26:54 GMT 2023 , Edited by admin on Sat Dec 16 13:26:54 GMT 2023

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CAS

1807954-17-1

Created by admin on Sat Dec 16 13:26:54 GMT 2023 , Edited by admin on Sat Dec 16 13:26:54 GMT 2023

PRIMARY

From	To
1_22	1_96
1_152	1_208
1_269	1_329
1_375	1_433
2_22	2_96
2_152	2_208
2_269	2_329
2_375	2_433
3_23	3_88
3_136	3_196
4_23	4_88
4_136	4_196
1_228	3_216
2_228	4_216
1_234	2_234
1_237	2_237

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_305
N	2_305

Related Record Type Details


					R9HH0NDE2E

INFLUENZA A VIRUS WHOLE

TARGET ORGANISM->INHIBITOR

Comments:

fully human neutralizing monoclonal antibody against influenza A. 39.29 is a neutralizing monoclonal antibody that recognizes the hemagglutinin (HA) glycoprotein of all 16 subtypes and neutralized both group 1 and group 2 influenza A viruses.

Amount:


					56B215N9J9

INFLUENZA A HEMAGGLUTIN

TARGET -> INHIBITOR

Interaction Type:

BINDING

Amount:

Related Record Type Details


					6IRE1TI49I

GEDIVUMAB

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL