Trastuzumab Botidotin

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:13:59 GMT 2023` Edited by `admin` on `Sat Dec 16 14:13:59 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	6HUZ008AZX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Trastuzumab Botidotin

Official Name

English

A-166

Code

English

A166

Code

English

ANTI-HER2 ANTIBODY-DRUG CONJUGATE A166

Common Name

English

Immunoglobulin G1, anti-(human epidermal growth factor receptor HER2) (human-Mus musculus monoclonal rhuMab HER2 γ1-chain), disulfide with human-Mus musculus monoclonal rhuMab HER2 κ-chain, dimer, 188′′,188′′′-diamide with N-[4-(4-carboxy-1-p

Common Name

English

trastuzumab botidotin [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (receptor tyrosine-protein kinase erbB-2, epidermal growth factor receptor 2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody; conjugated to duostatin-5 (Duo-5) via a cleavabl

Common Name

English

A 166 [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

641118