SALVINORIN B

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H26O7
Molecular Weight	390.4269
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](O)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)C4=COC=C4)C(=O)OC

InChI

InChIKey=BLTMVAIOAAGYAR-CEFSSPBYSA-N

InChI=1S/C21H26O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-15,17,22H,4,6,8-9H2,1-3H3/t12-,13-,14-,15-,17-,20-,21-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H26O7
Molecular Weight	390.4269
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

CNS Activity

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Kappa opioid receptor 108 Target ID: CHEMBL237 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25937170	Agonist 2678		11.8 nM [EC50]

PubMed

Title	Date	PubMed
Analytical investigation of legal high products containing Salvia divinorum traded in smartshops and internet.	2014 Sep	25093918
A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.	2015 May 20	25937170
Role of Ventral Subiculum in Context-Induced Relapse to Alcohol Seeking after Punishment-Imposed Abstinence.	2016 Mar 16	26985037
Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons.	2018 Nov	30203849

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:32:52 GMT 2023` Edited by `admin` on `Sat Dec 16 15:32:52 GMT 2023`
Record UNII	6HNB6FRT7X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SALVINORIN B

Common Name

English

METHYL (2R,4AR,6AR,7S,9R,10AS,10BR)-2-(FURAN-3-YL)-6A,10B-DIMETHYL-9-OXIDANYL-4,10-BIS(OXIDANYLIDENE)-2,4A,5,6,7,8,9,10A-OCTAHYDRO-1H-BENZO(F)ISOCHROMENE-7-CARBOXYLATE

Systematic Name

English

(-)-SALVINORIN B

Common Name

English

DIVINORIN B

Common Name

English

2H-NAPHTHO(2,1-C)PYRAN-7-CARBOXYLIC ACID, 2-(3-FURANYL)DODECAHYDRO-9-HYDROXY-6A,10B-DIMETHYL-4,10-DIOXO-, METHYL ESTER, (2S,4AR,6AR,7R,9S,10AS,10BR)-

Systematic Name

English

SANGUINARINE (RG)

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID50465988

Created by admin on Sat Dec 16 15:32:52 GMT 2023 , Edited by admin on Sat Dec 16 15:32:52 GMT 2023

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FDA UNII

6HNB6FRT7X

Created by admin on Sat Dec 16 15:32:52 GMT 2023 , Edited by admin on Sat Dec 16 15:32:52 GMT 2023

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PUBCHEM

11440685

Created by admin on Sat Dec 16 15:32:52 GMT 2023 , Edited by admin on Sat Dec 16 15:32:52 GMT 2023

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CAS

92545-30-7

Created by admin on Sat Dec 16 15:32:52 GMT 2023 , Edited by admin on Sat Dec 16 15:32:52 GMT 2023

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