Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C13H26NO2S2.Cl |
| Molecular Weight | 327.934 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Cl-].C[N+](C)(C)CCOC(=O)CCCC[C@@H]1CCSS1
InChI
InChIKey=QMADNKDMPGZUKN-UTONKHPSSA-M
InChI=1S/C13H26NO2S2.ClH/c1-14(2,3)9-10-16-13(15)7-5-4-6-12-8-11-17-18-12;/h12H,4-11H2,1-3H3;1H/q+1;/p-1/t12-;/m1./s1
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C13H26NO2S2 |
| Molecular Weight | 292.481 |
| Charge | 1 |
| Count |
|
| Stereochemistry | EPIMERIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
THIOCTIC ACID, also known as alpha-lipoic acid, is a vitamin-like antioxidant that acts as a free-radical scavenger. It exists in two enantiomeric forms, R and S, being the R isoform an essential cofactor of four mitochondrial enzyme complexes. THIOCTIC ACID is available as an over-the-counter nutritional supplement and has been used nutritionally and clinically since the 1950s for various diseases and conditions.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie. | 1997 Mar |
|
| Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. | 2009 Oct |
|
| Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases. | 2014 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 11:18:47 GMT 2023
by
admin
on
Sat Dec 16 11:18:47 GMT 2023
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| Record UNII |
6HBG94710Z
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| Record Status |
Validated (UNII)
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| Record Version |
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1808266-58-1
Created by
admin on Sat Dec 16 11:18:47 GMT 2023 , Edited by admin on Sat Dec 16 11:18:47 GMT 2023
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300000020011
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6HBG94710Z
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92135660
Created by
admin on Sat Dec 16 11:18:47 GMT 2023 , Edited by admin on Sat Dec 16 11:18:47 GMT 2023
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
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| Related Record | Type | Details | ||
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METABOLITE ACTIVE -> PRODRUG |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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