FLUPROSTENOL SODIUM

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H28F3O6.Na
Molecular Weight	480.4498
Optical Activity	( + / - )
Defined Stereocenters	5 / 5
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].O[C@@H](COC1=CC(=CC=C1)C(F)(F)F)\C=C\[C@H]2[C@H](O)C[C@H](O)[C@@H]2C\C=C/CCCC([O-])=O

InChI

InChIKey=MUVLUMTZYKYXRV-KXXGZHCCSA-M

InChI=1S/C23H29F3O6.Na/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31;/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-14H2,(H,30,31);/q;+1/p-1/b3-1-,11-10+;/t16-,18-,19-,20+,21-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C23H28F3O6
Molecular Weight	457.46
Charge	-1
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	2
Optical Activity	UNSPECIFIED

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Niacin promotes adipogenesis by reducing production of anti-adipogenic PGF2α through suppression of C/EBPβ-activated COX-2 expression.	2011-04	21236357
Prostaglandins differently regulate FGF-2 and FGF receptor expression and induce nuclear translocation in osteoblasts via MAPK kinase.	2005-02	15654655
The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs.	2000-01-17	10634944
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.	1997-09	9313928

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:36:43 GMT 2025` Edited by `admin` on `Mon Mar 31 17:36:43 GMT 2025`
Record UNII	6H4ZY4O7NA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EQUIMATE

Preferred Name

English

FLUPROSTENOL SODIUM

Official Name

English

5-HEPTENOIC ACID, 7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)-1-BUTENYL)CYCLOPENTYL)-, (1.ALPHA.(Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.)-, SODIUM SALT, (±)-

Common Name

English

FLUPROSTENOL SODIUM [GREEN BOOK]

Common Name

English

(±)- SODIUM (Z)-7-((1R*,2R*,3R*,5S*)-3,5-DIHYDROXY-2-((E)-(3R*)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)OXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOATE

Systematic Name

English

ICI-80008

Code

English

FLUPROSTENOL SODIUM SALT [MI]

Common Name

English

FLUPROSTENOL SODIUM [USAN]

Common Name

English

ICI 80,008

Code

English

SODIUM FLUPROSTENOL

Common Name

English

FLUPROSTENOL SODIUM SALT

Common Name

English

FLUPROSTENOL SODIUM [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29705