Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H5Cl5O |
| Molecular Weight | 342.433 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=C(C=C1Cl)C2=CC(Cl)=C(Cl)C(Cl)=C2Cl
InChI
InChIKey=CGAILIYIKMFHPA-UHFFFAOYSA-N
InChI=1S/C12H5Cl5O/c13-7-3-5(1-2-9(7)18)6-4-8(14)11(16)12(17)10(6)15/h1-4,18H
| Molecular Formula | C12H5Cl5O |
| Molecular Weight | 342.433 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Detection and measurement of the agonistic activities of PCBs and mono-hydroxylated PCBs to the constitutive androstane receptor using a recombinant yeast assay. | 2015-10 |
|
| Lactational exposure to hydroxylated polychlorinated biphenyl (OH-PCB 106) causes hyperactivity in male rat pups by aberrant increase in dopamine and its receptor. | 2014-08 |
|
| Gene expression profiling to examine the thyroid hormone-disrupting activity of hydroxylated polychlorinated biphenyls in metamorphosing amphibian tadpole. | 2010-11-19 |
|
| Hydroxylated polychlorinated biphenyls (PCBs) interact with protein disulfide isomerase and inhibit its activity. | 2009-05 |
|
| Identification of the functional domain of thyroid hormone receptor responsible for polychlorinated biphenyl-mediated suppression of its action in vitro. | 2008-09 |
|
| Sulfonation of 17beta-estradiol and inhibition of sulfotransferase activity by polychlorobiphenylols and celecoxib in channel catfish, Ictalurus punctatus. | 2007-03-10 |
|
| Low dose hydroxylated PCB induces c-Jun expression in PC12 cells. | 2006-03 |
|
| UDP-glucuronosyltransferase isoforms catalyzing glucuronidation of hydroxy-polychlorinated biphenyls in rat. | 2005-10 |
|
| Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity. | 2004-12 |
|
| 2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor. | 2004-02-01 |
|
| Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. | 2000-05 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:43:03 GMT 2025
by
admin
on
Mon Mar 31 20:43:03 GMT 2025
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| Record UNII |
6GW073T1WI
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| Record Status |
Validated (UNII)
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| Record Version |
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Systematic Name | English | ||
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192190-09-3
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DTXSID60172792
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644180
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admin on Mon Mar 31 20:43:03 GMT 2025 , Edited by admin on Mon Mar 31 20:43:03 GMT 2025
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