U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C13H9BrClNO2
Molecular Weight 326.573
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BROMOCHLOROSALICYLANILIDE

SMILES

OC1=C(C=C(Br)C=C1)C(=O)NC2=CC=C(Cl)C=C2

InChI

InChIKey=QBSGXIBYUQJHMJ-UHFFFAOYSA-N
InChI=1S/C13H9BrClNO2/c14-8-1-6-12(17)11(7-8)13(18)16-10-4-2-9(15)3-5-10/h1-7,17H,(H,16,18)

HIDE SMILES / InChI
Molecular Formula C13H9BrClNO2
Molecular Weight 326.573
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Bromochlorosalicylanilide (Multifungin) is a bromsalan antifungal that has been applied topically. It may cause allergic contact dermatitis in some individuals.

Approval Year

Unknown
139,594

Targets

Primary TargetPharmacologyConditionPotency
Microsporum gypseum
2
Inhibitor
8,297
Trichophyton mentagrophytes
3
Inhibitor
8,297
Trichophyton rubrum
5
Inhibitor
8,297

Conditions

ConditionModalityTargetsHighest PhaseProduct
Mycoses
12
 Primary
Approved
8,429
Multifungin

PubMed

Patents

JP3553083B2
49
WO2014121343A1
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Topical
In Vitro Use Guide
The minimum fungistatic concentrations of Bromochlorosalicylanilide (Multifungin) against M. gypseum was 18000 ppm
Substance Class Chemical
Record UNII
6GK715PWMQ
Record Status Validated (UNII)
Record Version
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966