BROMOCHLOROSALICYLANILIDE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H9BrClNO2
Molecular Weight	326.573
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=C(C=C(Br)C=C1)C(=O)NC2=CC=C(Cl)C=C2

InChI

InChIKey=QBSGXIBYUQJHMJ-UHFFFAOYSA-N

InChI=1S/C13H9BrClNO2/c14-8-1-6-12(17)11(7-8)13(18)16-10-4-2-9(15)3-5-10/h1-7,17H,(H,16,18)

HIDE SMILES / InChI

Molecular Formula	C13H9BrClNO2
Molecular Weight	326.573
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3743047 | https://www.ncbi.nlm.nih.gov/pubmed/5056804
Curator's Comment: Description was created based on several sources, including https://books.google.ru/books?id=2o3sCAAAQBAJ&pg=PA350&lpg=PA350&dq=Multifungin retrieved from Allergic Reactions to Drugs edited by Alain L. de Weck, H. Bundgaard, p.350

Bromochlorosalicylanilide (Multifungin) is a bromsalan antifungal that has been applied topically. It may cause allergic contact dermatitis in some individuals.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Microsporum gypseum 2 Target ID: CHEMBL612945 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3729389	Inhibitor 8504
Trichophyton mentagrophytes 3 Target ID: CHEMBL613162 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3729389	Inhibitor 8504
Trichophyton rubrum 5 Target ID: CHEMBL612649 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3729389	Inhibitor 8504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Mycoses 12 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5056804 https://www.ncbi.nlm.nih.gov/pubmed/13674390	Primary		Approved 8583	Multifungin Approved Use Fungal infections

PubMed

Title	Date	PubMed
Relationship between the structure and antimycobacterial activity of substituted salicylanilides.	2003-03	12666254

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Topical

In Vitro Use Guide

The minimum fungistatic concentrations of Bromochlorosalicylanilide (Multifungin) against M. gypseum was 18000 ppm

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:17:04 GMT 2025` Edited by `admin` on `Mon Mar 31 19:17:04 GMT 2025`
Record UNII	6GK715PWMQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-526297

Preferred Name

English

BROMOCHLOROSALICYLANILIDE

Systematic Name

English

CLOBROMSALAN

Common Name

English

SALICYLANILIDE, 5-BROMO-4'-CHLORO-

Systematic Name

English

SALIFUNGEN

Common Name

English

BROMOSALICYLCHLORANILIDE [MI]

Common Name

English

SALIFUNGIN

Common Name

English

Bromochlorosalicylanilide [WHO-DD]

Common Name

English

BROMOSALICYCHLORANILIDINE

Common Name

English

5-BROMOSALICYL-4'-CHLOROANILIDE

Common Name

English

5-BROMO-4'-CHLOROSALICYLANILIDE

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

D01AE01