Lumistobart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 18:26:14 GMT 2025` Edited by `admin` on `Wed Apr 02 18:26:14 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	6GCR77W6UZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BR-105

Preferred Name

English

Lumistobart

Official Name

English

lumistobart [INN]

Common Name

English

Immunoglobulin G1, anti-(human signal regulatory protein ?) (human-Mus musculus monoclonal BR105 ?1-chain), disulfide with human-Mus musculus monoclonal BR105 ?-chain, dimer

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens SIRPA (signal regulatory protein alpha, SHPS1, protein tyrosine phosphatase nonreceptor type substrate 1, PTPNS1, SIRP, SIRP alpha, CD172a)], humanized monoclonal antibody

Common Name

English

BR105

Code

English

H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV4-31*02 (93.9%) -(IGHD) -IGHJ4*01 (86.7%) L123>T (113), CDR-IMGT [9.7.11] (26-34.52-58.97-107)) (1-118) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v29 CH2 A84.4 (CH1 R

Common Name

English

Code System Code Type Description

CAS

2851923-91-4