TALMETACIN

Details

Stereochemistry	RACEMIC
Molecular Formula	C27H20ClNO6
Molecular Weight	489.904
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C=C1)N(C(=O)C3=CC=C(Cl)C=C3)C(C)=C2CC(=O)OC4OC(=O)C5=CC=CC=C45

InChI

InChIKey=XYRIRLDHOQSNLW-UHFFFAOYSA-N

InChI=1S/C27H20ClNO6/c1-15-21(14-24(30)34-27-20-6-4-3-5-19(20)26(32)35-27)22-13-18(33-2)11-12-23(22)29(15)25(31)16-7-9-17(28)10-8-16/h3-13,27H,14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C27H20ClNO6
Molecular Weight	489.904
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA1147&lpg=PA1147&dq=TALMETACIN&source=bl&ots=6JUgo7Uwpz&sig=ACfU3U3XbB1-ZmSP6Tas5dQAh_pv8mQhew&hl=ru&sa=X&ved=2ahUKEwjo8sXbn5njAhUFwMQBHQ6lCDE4FBDoATACegQICRAB#v=onepage&q=TALMETACIN&f=false | https://adisinsight.springer.com/drugs/800008100

Talmetacin is a cyclo-oxygenase inhibitor that was studied as an analgesic and antipyretic agent. This drug was studied in Argentina in patients with rheumatic disorders. However, further development of talmetacin is not available.

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:56:00 GMT 2025` Edited by `admin` on `Wed Apr 02 09:56:00 GMT 2025`
Record UNII	6FY017I6S7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BA 7605-06

Preferred Name

English

TALMETACIN

Official Name

English

(±)-PHTHALIDYL 1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETATE

Common Name

English

1H-INDOLE-3-ACETIC ACID, 1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-, 1,3-DIHYDRO-3-OXO-1-ISOBENZOFURANYL ESTER

Systematic Name

English

talmetacin [INN]

Common Name

English

TALMETACIN [USAN]

Common Name

English

BA-7605-06

Code

English

1H-INDOLE-3-ACETIC ACID, 1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-, 1,3-DIHYDRO-3-OXO-1-ISOBENZOFURANYL ESTER, (±)-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257