PHENYLTHIOUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8N2S
Molecular Weight	152.217
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=S)NC1=CC=CC=C1

InChI

InChIKey=FULZLIGZKMKICU-UHFFFAOYSA-N

InChI=1S/C7H8N2S/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10)

HIDE SMILES / InChI

Molecular Formula	C7H8N2S
Molecular Weight	152.217
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Characterization of phenoloxidase activity in venom from the ectoparasitoid Nasonia vitripennis (Walker) (Hymenoptera: Pteromalidae).	2007-02	17054979
Differences in smoking-related variables based on phenylthiocarbamide "taster" status.	2006-12	16580152
Epidermal transient down-regulation of retinol-binding protein 4 and mirror expression of apolipoprotein Eb and estrogen receptor 2a during zebrafish fin and scale development.	2006-11	16929533
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon.	2006-11	16728727
Dose-dependent effects of chemical immobilization on the heart rate of embryonic zebrafish.	2006-10	17008908
A potential novel mechanism involving connexin 43 gap junction for control of sertoli cell proliferation by thyroid hormones.	2006-10	16823880
Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels.	2006-10	16707556
Modeling the human PTC bitter-taste receptor interactions with bitter tastants.	2006-09	16607493
Associations of phenylthiocarbamide tasting to alcohol problems and family history of alcoholism differ by gender.	2006-06-30	16712955
s-Benzylthiuronium PVC matrix membrane sensor for potentiometric determination of cationic surfactants in some pharmaceutical formulation.	2006-06-16	16540278
The human sweet tooth.	2006-06-15	16934118
Human glioblastoma ADF cells express tyrosinase, L-tyrosine hydroxylase and melanosomes and are sensitive to L-tyrosine and phenylthiourea.	2006-06	16447258
The relationship between phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) taster status and taste thresholds for sucrose and quinine.	2006-05	16297856
Independent evolution of bitter-taste sensitivity in humans and chimpanzees.	2006-04-13	16612383
Conformational preferences and internal rotation in alkyl- and phenyl-substituted thiourea derivatives.	2006-04-13	16599434
Phenylthiocarbamide: a 75-year adventure in genetics and natural selection.	2006-04	16636110
Regulation of melanin synthesis by selenium-containing carbohydrates.	2006-03	16508177
A unique NH-spacer for N-benzamidothiourea based anion sensors. Substituent effect on anion sensing of the ICT dual fluorescent N-(p-dimethylaminobenzamido)-N'-arylthioureas.	2006-02-21	16467936
Synthesis and in vitro antitubercular activity of some 1-[(4-sub)phenyl]-3-(4-{1-[(pyridine-4-carbonyl)hydrazono]ethyl}phenyl)thiourea.	2006-02-15	16303302
Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents.	2006-01-01	16216504
Purification and characterization of phenoloxidase from crab Charybdis japonica.	2006-01	15927483
Clinically useful vanilloid receptor TRPV1 antagonists: just around the corner (or too early to tell)?	2006	16697897
Associations between phenylthiocarbamide gene polymorphisms and cigarette smoking.	2005-12	16298720
Laccase-type phenoloxidase in salivary glands and watery saliva of the green rice leafhopper, Nephotettix cincticeps.	2005-12	16216260
1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.	2005-11-17	16279809
Founder mutations.	2005-10	16196257
Alkylating benzamides with melanoma cytotoxicity: role of melanin, tyrosinase, intracellular pH and DNA interaction.	2005-10	16179865
Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci.	2005-09	16086309
Purification and characterisation of phenoloxidase from amphioxus Branchiostoma belcheri tsingtauense.	2005-08	15752652
Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat.	2005-07-14	15886333
Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar.	2005-07	16103917
Genetic analysis of reproduction in the Buryat populations.	2005-07	16079578
Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli.	2005-06-20	15967025
Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	2005-06-06	15938754
The relationship between PTC taster status and taste thresholds in young adults.	2005-06	15897858
Phenylthiocarbamide produces conditioned taste aversions in mice.	2005-06	15800216
Phenylthiocarbamide perception in patients with schizophrenia and first-degree family members.	2005-04	15800154
Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation.	2005-04	15760341
Genetics of individual differences in bitter taste perception: lessons from the PTC gene.	2005-04	15733260
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception.	2005-02-22	15723792
S-oxygenation of thiocarbamides I: Oxidation of phenylthiourea by chlorite in acidic media.	2005-02-17	16833417
1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents.	2005-02-01	15664862
Highly conserved non-coding sequences are associated with vertebrate development.	2005-01	15630479
Thermogravimetric studies of benzoylthiourea-modified MCM-41 after adsorption of mercury ions from aqueous solutions.	2005-01	15614361
Human taste genetics.	2005	16124860
Phenoloxidase activity in Apis mellifera honey bee pupae, and ecdysteroid-dependent expression of the prophenoloxidase mRNA.	2004-12	15544939
Structure-activity relationship of S-benzylisothiourea derivatives to induce spherical cells in Escherichia coli.	2004-11	15564663
Optical physiology and locomotor behaviors of wild-type and nacre zebrafish.	2004	15602880
A new member of the GM130 golgin subfamily is expressed in the optic lobe anlagen of the metamorphosing brain of Manduca sexta.	2003	15841250
Storage hexamer utilization in Manduca sexta.	2003	15841242

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:56:48 GMT 2025` Edited by `admin` on `Mon Mar 31 17:56:48 GMT 2025`
Record UNII	6F82C6Q54C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PHENYLTHIOUREA

Systematic Name

English

1-PHENYL-2-THIOUREA

Preferred Name

English

PHENYLTHIOCARBAMIDE

Common Name

English

1-PHENYL-2-THIOUREA [HSDB]

Common Name

English

NSC-5779

Code

English

N-PHENYLTHIOUREA [MI]

Common Name

English

Code System Code Type Description

MERCK INDEX

m8694