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Description

Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
Surgicide

Approved Use

Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed
PubMed

PubMed

TitleDatePubMed
Thyroid adaptation to chronic tetraglycine hydroperiodide water purification tablet use.
1995 Jan
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.
1996 Mar
Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies.
1997 Jul
Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine.
2005 Nov
The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.
2006 Mar
Antiseptics, iodine, povidone iodine and traumatic wound cleansing.
2006 Nov
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.
2007 Apr
Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment.
2007 Mar
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
2007 Nov
Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography.
2007 Oct 1
Patents

Patents

20030153532
9
Substance Class Polymer
Created
by admin
on Sat Dec 16 08:13:11 GMT 2023
Edited
by admin
on Sat Dec 16 08:13:11 GMT 2023
Record UNII
6E43AWY083
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IODINE POVACRYLEX
ORANGE BOOK   USAN   WHO-DD  
USAN  
Official Name English
IODINE POVACRYLEX COMPONENT OF DURAPREP
Brand Name English
DURAPREP COMPONENT IODINE POVACRYLEX
Brand Name English
METHYL 2-METHYLPROP-2-ENOATE POLYMER WITH 1-ETHENYLPYRROLIDIN-2-ONE AND ISOOCTYL PROP-2-ENOATE COMPOUND WITH DIIODINE AND SODIUM IODIDE
Common Name English
Iodine povacrylex [WHO-DD]
Common Name English
IODINE POVACRYLEX [USAN]
Common Name English
IODINE POVACRYLEX [ORANGE BOOK]
Common Name English
2-PROPENOIC ACID, 2-METHYL-, METHYL ESTER, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE AND ISOOCTYL 2-PROPENOATE, COMPOUND WITH IODINE AND SODIUM IODIDE (NAI)
Common Name English
Code System Code Type Description
FDA UNII
6E43AWY083
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
EPA CompTox
DTXSID501027731
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
RXCUI
692863
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY RxNorm
NCI_THESAURUS
C166931
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
USAN
RR-25
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
DRUG BANK
DB09537
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
CAS
845736-10-9
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
DAILYMED
6E43AWY083
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
SMS_ID
300000044487
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
ChEMBL
CHEMBL1201721
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
Display Structure of IODINE POVACRYLEX
Related Record Type Details
Structure of Iodine
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
Sodium iodide F5WR8N145C
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
NIH
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