Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The susceptibility of the fetus and child to chemical pollutants. Special susceptibility of the host to chemical agents: endocrinologic considerations. | 1974 May |
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| [Necrotizing hepatitis with a fatal outcome after carbimazole therapy]. | 1993 Oct 22 |
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| Subfulminant hepatitis requiring liver transplantation after benzarone administration. | 1994 Jun |
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| Thyroid adaptation to chronic tetraglycine hydroperiodide water purification tablet use. | 1995 Jan |
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| Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis. | 1996 Mar |
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| Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies. | 1997 Jul |
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| Adverse reactions to nonionic iodine in contrast-enhanced computed tomography: usefulness of monitoring vital signs. | 1998 Jul |
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| Anti-goitrous effect of lecithin-bound iodine in propylthiouracil treated rats. | 2000 Jun |
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| Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin. | 2001 Feb |
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| Effects of selenium and iodine on the expression of c-fos and c-jun mRNA and their proteins in cultured rat hippocampus neurons. | 2002 Jun |
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| Effects of selenium and iodine on c-fos and c-jun mRNA and their protein expressions in cultured rat hippocampus cells. | 2002 Winter |
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| Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine. | 2003 Apr |
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| Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue. | 2003 Jan |
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| Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa. | 2004 Feb |
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| [Effect of high-iodine intake on MBP mRNA expression in cerebrum of filial mice and selenium intervention]. | 2005 Jul |
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| Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine. | 2005 Nov |
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| Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma. | 2005 Oct |
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| Effect of selenium supplementation on activity and mRNA expression of type 1 deiodinase in mice with excessive iodine intake. | 2006 Aug |
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| Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. | 2006 Aug 1 |
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| Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not hemoglobin in children in Cote d'Ivoire. | 2006 Jul |
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| Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway. | 2006 Jul 14 |
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| Antiseptics, iodine, povidone iodine and traumatic wound cleansing. | 2006 Nov |
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| Comparative cytotoxicity of high-osmolar and low-osmolar contrast media on HKCs in vitro. | 2006 Nov-Dec |
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| The treatment of Graves' disease in children. | 2006 Sep |
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| Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma. | 2007 Apr |
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| Goiter and other iodine deficiency disorders: A systematic review of epidemiological studies to deconstruct the complex web. | 2007 Jan |
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| [Effects of iodine excess and selenium supplement on the levels of thyroid hormone and its receptor expression in filial cerebrum of mice]. | 2007 Mar |
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| Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment. | 2007 Mar |
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| Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). | 2007 Nov |
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| Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography. | 2007 Oct 1 |
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| [Suggestions for prevention of adverse reactions after intravasal administration of iodinated contrast media]. | 2008 |
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| [The effects of iodine/selenium on the function of antigen presentation of peritoneal macrophages in rats]. | 2008 Jul |
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| Gadolinium and kidney disease: are your patients at risk? | 2008 Mar-Apr |
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| Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency. | 2009 Dec |
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| A blinded, randomized, palatability study comparing variations of 2 popular field water disinfection tablets. | 2011 Dec |
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| I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident. | 2011 Jul |
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| The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat. | 2012 Aug |
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| Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice. | 2012 Sep 1 |
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| Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry. | 2013 Jan |
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| Developmental iodine deficiency delays the maturation of newborn granule neurons associated with downregulation of p35 in postnatal rat hippocampus. | 2014 Aug |
Patents
| Substance Class |
Polymer
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ACTIVE MOIETY |
Agent Modifications
| Modification Process | Modification Role | Modification Type | Amount | Fragment Name | Fragment ID |
|---|---|---|---|---|---|
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Sodium iodide | F5WR8N145C |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
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