U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Surgicide

Approved Use

Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed
PubMed

PubMed

TitleDatePubMed
[Necrotizing hepatitis with a fatal outcome after carbimazole therapy].
1993 Oct 22
Subfulminant hepatitis requiring liver transplantation after benzarone administration.
1994 Jun
Thyroid adaptation to chronic tetraglycine hydroperiodide water purification tablet use.
1995 Jan
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.
1996 Mar
Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineutrophil cytoplasmic autoantibodies.
1997 Jul
Adverse reactions to nonionic iodine in contrast-enhanced computed tomography: usefulness of monitoring vital signs.
1998 Jul
Anti-goitrous effect of lecithin-bound iodine in propylthiouracil treated rats.
2000 Jun
Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin.
2001 Feb
Effects of selenium and iodine on the expression of c-fos and c-jun mRNA and their proteins in cultured rat hippocampus neurons.
2002 Jun
Effects of selenium and iodine on c-fos and c-jun mRNA and their protein expressions in cultured rat hippocampus cells.
2002 Winter
Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue.
2003 Jan
Studies on experimental iodine allergy: 3. Low molecular weight elicitogenic antigens of iodine allergy.
2004 May
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.
2005 Oct
Effect of selenium supplementation on activity and mRNA expression of type 1 deiodinase in mice with excessive iodine intake.
2006 Aug
The treatment of Graves' disease in children.
2006 Sep
Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment.
2007 Mar
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
2007 Nov
[Suggestions for prevention of adverse reactions after intravasal administration of iodinated contrast media].
2008
[The effects of iodine/selenium on the function of antigen presentation of peritoneal macrophages in rats].
2008 Jul
Gadolinium and kidney disease: are your patients at risk?
2008 Mar-Apr
A blinded, randomized, palatability study comparing variations of 2 popular field water disinfection tablets.
2011 Dec
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.
2012 Aug
Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
2012 Sep 1
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.
2013 Jan
Patents

Patents

Substance Class Polymer
Created
by admin
on Sat Dec 16 08:13:11 GMT 2023
Edited
by admin
on Sat Dec 16 08:13:11 GMT 2023
Record UNII
6E43AWY083
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IODINE POVACRYLEX
ORANGE BOOK   USAN   WHO-DD  
USAN  
Official Name English
IODINE POVACRYLEX COMPONENT OF DURAPREP
Brand Name English
DURAPREP COMPONENT IODINE POVACRYLEX
Brand Name English
METHYL 2-METHYLPROP-2-ENOATE POLYMER WITH 1-ETHENYLPYRROLIDIN-2-ONE AND ISOOCTYL PROP-2-ENOATE COMPOUND WITH DIIODINE AND SODIUM IODIDE
Common Name English
Iodine povacrylex [WHO-DD]
Common Name English
IODINE POVACRYLEX [USAN]
Common Name English
IODINE POVACRYLEX [ORANGE BOOK]
Common Name English
2-PROPENOIC ACID, 2-METHYL-, METHYL ESTER, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE AND ISOOCTYL 2-PROPENOATE, COMPOUND WITH IODINE AND SODIUM IODIDE (NAI)
Common Name English
Code System Code Type Description
FDA UNII
6E43AWY083
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
EPA CompTox
DTXSID501027731
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
RXCUI
692863
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY RxNorm
NCI_THESAURUS
C166931
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
USAN
RR-25
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
DRUG BANK
DB09537
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
CAS
845736-10-9
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
DAILYMED
6E43AWY083
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
SMS_ID
300000044487
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
ChEMBL
CHEMBL1201721
Created by admin on Sat Dec 16 08:13:11 GMT 2023 , Edited by admin on Sat Dec 16 08:13:11 GMT 2023
PRIMARY
Display Structure of IODINE POVACRYLEX
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
Sodium iodide F5WR8N145C
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL