CLOTICASONE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H27ClF2O4S
Molecular Weight	460.962
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)SCCl)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])C[C@H](F)C4=CC(=O)C=C[C@]34C

InChI

InChIKey=ANLWAEZHUOEOTI-GQKYHHCASA-N

InChI=1S/C22H27ClF2O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H27ClF2O4S
Molecular Weight	460.962
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA306&redir_esc=y#v=onepage&q=Cloticasone&f=false | https://patents.google.com/patent/GB2088877B/en

Cloticasone is a synthetic glucocorticoid corticosteroid, an analog of fluticasone. Cloticasone was discovered by Glaxo in the 1980s and claimed to be useful as an antiinflammation agent.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:35:39 UTC 2023` Edited by `admin` on `Sat Dec 16 16:35:39 UTC 2023`
Record UNII	6CN32ZUQ4X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOTICASONE

Official Name

English

S-(CHLOROMETHYL) 6.ALPHA.,9-DIFLUORO-11.BETA.,17-DIHYDROXY-16.ALPHA.-METHYL-3-OXOANDROSTA-1,4-DIENE-17.BETA.-CARBOTHIOATE

Common Name

English

cloticasone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521