U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:44:16 GMT 2023
Edited
by admin
on Sat Dec 16 13:44:16 GMT 2023
Protein Type REGULATOR PROTEIN
Protein Sub Type ANTI-APOPTOCTIC REGULATORY PROTEIN
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
6C7ZU4I3AH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3
Common Name English
CELLULAR INHIBITOR OF APOPTOSIS 2
Common Name English
HIAP-1
Common Name English
INHIBITOR OF APOPTOSIS PROTEIN 1
Common Name English
MIHC
Common Name English
APOPTOSIS INHIBITOR 2
Common Name English
BIRC3
Common Name English
RING FINGER PROTEIN 49
Common Name English
C-IAP2
Common Name English
API2
Common Name English
TNFR2-TRAF-SIGNALING COMPLEX PROTEIN 1
Common Name English
IAP HOMOLOG C
Common Name English
HIAP1
Common Name English
RING-TYPE E3 UBIQUITIN TRANSFERASE BIRC3
Common Name English
RNF49
Common Name English
Code System Code Type Description
UNIPROT
Q13489
Created by admin on Sat Dec 16 13:44:16 GMT 2023 , Edited by admin on Sat Dec 16 13:44:16 GMT 2023
PRIMARY
FDA UNII
6C7ZU4I3AH
Created by admin on Sat Dec 16 13:44:16 GMT 2023 , Edited by admin on Sat Dec 16 13:44:16 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
small molecule second mitochondrial activator of caspase (SMAC) mimetic, which both disengages IAPs from caspases and induces proteasomal degradation of cIAP-1 and -2, resulting in altered signaling through the NFκB pathway.
BINDING
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL