P2X PURINOCEPTOR 7

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 03:05:31 GMT 2025` Edited by `admin` on `Wed Apr 02 03:05:31 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	6C4N8MNM6I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

P2X PURINOCEPTOR 7

Common Name

English

ATP RECEPTOR

Preferred Name

English

P2Z RECEPTOR

Common Name

English

PURINERGIC RECEPTOR

Common Name

English

P2X7

Common Name

English

Code System Code Type Description

PHAROS

Q99572

Created by admin on Wed Apr 02 03:05:31 GMT 2025 , Edited by admin on Wed Apr 02 03:05:31 GMT 2025

PRIMARY

FDA UNII

6C4N8MNM6I

Created by admin on Wed Apr 02 03:05:31 GMT 2025 , Edited by admin on Wed Apr 02 03:05:31 GMT 2025

PRIMARY

UNIPROT

Q99572

Created by admin on Wed Apr 02 03:05:31 GMT 2025 , Edited by admin on Wed Apr 02 03:05:31 GMT 2025

PRIMARY

From	To
1_119	1_168
1_129	1_152
1_135	1_162
1_216	1_226
1_260	1_269

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_187
N	1_202
N	1_213
N	1_241
N	1_284

Related Record Type Details


					32524GLF40

JNJ-54175446

INHIBITOR -> TARGET


					T8B02RAU3C

CE-224535

INHIBITOR -> TARGET

Amount:


					S02R2AF9AV

JNJ-64413739

INHIBITOR -> TARGET


					POV7O5DM8F

SMW-139 C-11

RADIOLIGAND->TARGET


					L22UF6D1CU

SMW-139

INHIBITOR -> TARGET


					5R2KSX4P44

JNJ-64413739 F-18

RADIOLIGAND->TARGET

Qualification:

Ki

Amount:


					T1V3OH20HG

GSK-1482160

INHIBITOR -> TARGET

Amount:


					B7YN3CQ7S7

Zanvipixant

INHIBITOR -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_343]				TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO ACID SUBSTITUTION	[1_125] [1_133]

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL