U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:28:09 GMT 2023
Edited
by admin
on Sat Dec 16 14:28:09 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
6BUL1G4D60
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
UBAMATAMAB
INN   USAN  
Official Name English
UBAMATAMAB [USAN]
Common Name English
REGN4018
Code English
REGN-4018
Code English
ANTI-MUC16/CD3 BITE ANTIBODY REGN4018
Common Name English
Ubamatamab [WHO-DD]
Common Name English
BISPECIFIC T-CELL ENGAGER ANTIBODY REGN4018
Common Name English
MUC16XCD3 BISPECIFIC T-CELL ENGAGER REGN4018
Common Name English
IMMUNOGLOBULIN G4 (232-PROLINE,237-PROLINE,238-VALINE,239-ALANINE,DE-240-GLYCINE,439-ARGININE,440-PHENYLALANINE,449-PROLINE), ANTI-(HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) (HUMAN MONOCLONAL REGN4018 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REGN4018 .K
Systematic Name English
IMMUNOGLOBULIN G4-KAPPA BISPECIFIC: ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN, CD3E ANTIGEN)) AND ANTI-(HOMO SAPIENS MUCIN-16 (OVARIAN CANCER-RELATED TUMOR MARKER CA125, OVARIAN CARCIN
Systematic Name English
ubamatamab [INN]
Common Name English
Code System Code Type Description
FDA UNII
6BUL1G4D60
Created by admin on Sat Dec 16 14:28:10 GMT 2023 , Edited by admin on Sat Dec 16 14:28:10 GMT 2023
PRIMARY
USAN
HI-26
Created by admin on Sat Dec 16 14:28:10 GMT 2023 , Edited by admin on Sat Dec 16 14:28:10 GMT 2023
PRIMARY
NCI_THESAURUS
C153129
Created by admin on Sat Dec 16 14:28:10 GMT 2023 , Edited by admin on Sat Dec 16 14:28:10 GMT 2023
PRIMARY NCIT
CAS
2305629-50-7
Created by admin on Sat Dec 16 14:28:10 GMT 2023 , Edited by admin on Sat Dec 16 14:28:10 GMT 2023
PRIMARY
INN
11679
Created by admin on Sat Dec 16 14:28:10 GMT 2023 , Edited by admin on Sat Dec 16 14:28:10 GMT 2023
PRIMARY
From To
4_135 4_195
4_23 4_88
3_135 3_195
3_23 3_88
2_363 2_421
2_257 2_317
2_144 2_200
2_131 4_215
2_22 2_96
1_370 1_428
1_264 1_324
1_233 2_226
1_230 2_223
1_151 1_207
1_138 3_215
1_22 1_96
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_293
N 2_300
Related Record Type Details
TARGET->LIGAND
TARGET -> ACTIVATOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL