Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H9NO |
| Molecular Weight | 195.2167 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1C2=C(NC3=C1C=CC=C3)C=CC=C2
InChI
InChIKey=FZEYVTFCMJSGMP-UHFFFAOYSA-N
InChI=1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)
| Molecular Formula | C13H9NO |
| Molecular Weight | 195.2167 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Presence and fate of carbamazepine, oxcarbazepine, and seven of their metabolites at wastewater treatment plants. | 2009-04 |
|
| Synthesis of N-4-butylamine acridone and its use as fluorescent probe for ctDNA. | 2009-01-01 |
|
| Biotransformation of acridine by Mycobacterium vanbaalenii. | 2009-01 |
|
| Synthesis, cytotoxic activity, and mechanism of action of furo[2,3-c]acridin-6-one and benzo[b]furo[3,2-h]acridin-6-one analogues of psorospermin and acronycine. | 2008-11-27 |
|
| Chloro acridone derivatives as cytotoxic agents active on multidrug-resistant cell lines and their duplex DNA complex studies by electrospray ionization mass spectrometry. | 2008-11-25 |
|
| Hybridization biosensor using 2-nitroacridone as electrochemical indicator for detection of short DNA species of Chronic Myelogenous Leukemia. | 2008-11-15 |
|
| New acridone-4-carboxylic acid derivatives as potential inhibitors of hepatitis C virus infection. | 2008-10-01 |
|
| Potential anti-allergic acridone alkaloids from the roots of Atalantia monophylla. | 2008-10 |
|
| Application of chitin and chitosan as elicitors of coumarins and fluoroquinolone alkaloids in Ruta graveolens L. (common rue). | 2008-10 |
|
| Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones. | 2008-09-15 |
|
| Design, synthesis and preliminary biological evaluation of acridine compounds as potential agents for a combined targeted chemo-radionuclide therapy approach to melanoma. | 2008-08-15 |
|
| Novel fluorinated acridone derivatives. Part 1: synthesis and evaluation as potential anticancer agents. | 2008-07-15 |
|
| Acridone-tagged DNA as a new probe for DNA detection by fluorescence resonance energy transfer and for mismatch DNA recognition. | 2008-07-15 |
|
| Unusually divergent 4-coumarate:CoA-ligases from Ruta graveolens L. | 2008-07 |
|
| Chronic exposure of the oligochaete Lumbriculus variegatus to polycyclic aromatic compounds (PACs): bioavailability and effects on reproduction. | 2008-05-01 |
|
| Cooperativity in intramolecular bifurcated hydrogen bonds: an ab initio study. | 2008-04-17 |
|
| Life cycle responses of the midge Chironomus riparius to polycyclic aromatic compound exposure. | 2008-03 |
|
| Quinoline, quinazoline and acridone alkaloids. | 2008-02 |
|
| Anthranilate N-methyltransferase, a branch-point enzyme of acridone biosynthesis. | 2008-02 |
|
| SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series. | 2008-01-01 |
|
| Combining G-quadruplex targeting motifs on a single peptide nucleic acid scaffold: a hybrid (3+1) PNA-DNA bimolecular quadruplex. | 2008 |
|
| Synthesis and evaluation of N-substituted acridones as antiviral agents against haemorrhagic fever viruses. | 2008 |
|
| Substrate arrays for fluorescence-based enzyme fingerprinting and high-throughput screening. | 2008 |
|
| Design, synthesis and biological evaluation of new oligopyrrole carboxamides linked with tricyclic DNA-intercalators as potential DNA ligands or topoisomerase inhibitors. | 2007-06 |
|
| Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2. | 2007-04-15 |
|
| Modulation of P-glycoprotein activity by acridones and coumarins from Citrus sinensis. | 2007-04 |
|
| Acridine and acridone derivatives, anticancer properties and synthetic methods: where are we now? | 2007-03 |
|
| Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa. | 2007-03 |
|
| Chemico-enzymatic synthesis of a new fluorescent-labeled DNA by PCR with a thymidine nucleotide analogue bearing an acridone derivative. | 2007-02-01 |
|
| Quinoline, quinazoline and acridone alkaloids. | 2007-02 |
|
| An acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata. | 2007-02 |
|
| [From acronycine to benzo-[b]-acronycine derivatives: potent antitumor agents]. | 2007-01 |
|
| In vitro cytotoxicity activity on several cancer cell lines of acridone alkaloids and N-phenylethyl-benzamide derivatives from Swinglea glutinosa (Bl.) Merr. | 2007-01 |
|
| Investigation of cytotoxic activity on human cancer cell lines of arborinine and furanoacridones isolated from Ruta graveolens. | 2007-01 |
|
| Synthesis and structure-activity studies of peptide-acridine/acridone conjugates. | 2007 |
|
| Electroenzymatic polypyrrole-intercalator sensor for the determination of West Nile virus cDNA. | 2006-10-01 |
|
| Evaluation and lead optimization of anti-malarial acridones. | 2006-09 |
|
| Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity. | 2006-08-15 |
|
| Synthesis of acridone derivatives using polymer-supported palladium and scandium catalysts. | 2006-07-11 |
|
| Synthesis and anti-BVDV activity of acridones as new potential antiviral agents. | 2006-04-20 |
|
| Spectrophotometric determination and computational evaluation of the rates of hydrolysis of 9-amino-substituted acridines. | 2006-03-28 |
|
| Anionic N-fries rearrangement of N-carbamoyl diarylamines to anthranilamides. Methodology and application to acridone and pyranoacridone alkaloids. | 2006-03-16 |
|
| Alpha-glucosidase inhibitory and antioxidant acridone alkaloids from the stem bark of Oriciopsis glaberrima ENGL. (Rutaceae). | 2006-03 |
|
| Sensitization of multidrug resistant (MDR) cancer cells to vinblastine by novel acridones: correlation between anti-calmodulin activity and anti-MDR activity. | 2006-01 |
|
| Design, synthesis and antiproliferative activity of some new azapyranoxanthenone aminoderivatives. | 2006-01 |
|
| Synthesis and properties of acridone-labeled base-discriminating fluorescent (BDF) nucleosides. | 2006 |
|
| Synthesis and property of DNA labeled with fluorescent acridone. | 2006 |
|
| Liquid chromatography-electrospray mass spectrometry determination of carbamazepine, oxcarbazepine and eight of their metabolites in human plasma. | 2005-12-15 |
|
| Astonishing diversity of natural surfactants: 6. Biologically active marine and terrestrial alkaloid glycosides. | 2005-11 |
|
| Quinoline, quinazoline and acridone alkaloids. | 2005-10 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:30:04 GMT 2025
by
admin
on
Mon Mar 31 19:30:04 GMT 2025
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| Record UNII |
6BK306GUQA
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| Record Status |
Validated (UNII)
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| Record Version |
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1483185
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2015
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C041300
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DTXSID8060371
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6BK306GUQA
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209-434-7
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ACRIDONE
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578-95-0
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408196
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