SAPABLURSEN SODIUM

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 16:19:18 GMT 2023` Edited by `admin` on `Sat Dec 16 16:19:18 GMT 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	6BGP5P5P2C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SAPABLURSEN SODIUM

Official Name

English

ISIS 702843 SODIUM

Code

English

IONIS TMPRSS6-LRX SODIUM

Common Name

English

ISIS-702843 SODIUM

Code

English

IONIS-TMPRSS6-LRX SODIUM

Common Name

English

DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))RA-T-SP-T-SP-M5C-SP-M5C-SP-A-SP-A-SP-A-SP-G-SP-G-SP-G-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R

Systematic Name

English

Code System Code Type Description

FDA UNII

6BGP5P5P2C

Created by admin on Sat Dec 16 16:19:18 GMT 2023 , Edited by admin on Sat Dec 16 16:19:18 GMT 2023

PRIMARY

NCI_THESAURUS

C186388

Created by admin on Sat Dec 16 16:19:18 GMT 2023 , Edited by admin on Sat Dec 16 16:19:18 GMT 2023

PRIMARY

CAS

2273008-00-5

Created by admin on Sat Dec 16 16:19:18 GMT 2023 , Edited by admin on Sat Dec 16 16:19:18 GMT 2023

PRIMARY

SMS_ID

300000044773

Created by admin on Sat Dec 16 16:19:18 GMT 2023 , Edited by admin on Sat Dec 16 16:19:18 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
	1_3-1_6;1_17-1_19	7 / 19
Sodium Phosporothioate	1_2;1_7-1_16;1_20	12 / 19

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Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS	UNSPECIFIED SUBSTANCE	708789d3 (not in database)
NUCLEOSIDE_SUBSTITUTION	[1_2] [1_3] [1_4] [1_20]	SITE_SPECIFIC	THYMINE	QR26YLT7LT
NUCLEOSIDE BASE SUBSTITUTION	[1_8] [1_9] [1_16] [1_19]	SITE_SPECIFIC	5-METHYLCYTOSINE	6R795CQT4H