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Details

Stereochemistry ABSOLUTE
Molecular Formula C28H47IO
Molecular Weight 526.5767
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 6-IODOMETHYLCHOLESTEROL

SMILES

[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC(CI)=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C

InChI

InChIKey=VNZIOSXRDKNPQW-ROUDTPAMSA-N
InChI=1S/C28H47IO/c1-18(2)7-6-8-19(3)23-9-10-24-22-15-20(17-29)26-16-21(30)11-13-28(26,5)25(22)12-14-27(23,24)4/h18-19,21-25,30H,6-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,27-,28-/m1/s1

HIDE SMILES / InChI

Molecular Formula C28H47IO
Molecular Weight 526.5767
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 8 / 8
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
[Clinical values of adrenal scintigraphy by I-6-beta-iodomethyl-19-norcholesterol (123I-NCL) (author's transl)].
1982 Mar
Value of bowel preparation in adrenocortical scintigraphy with NP-59.
1983 Aug
[Effects of specific radioactivities and cholagogues on tissue distribution of 131I-6 beta-iodomethyl-19-norcholest-5(10)-en-3 beta-ol(NCL-6-131I) in rats].
1983 Jun
Application of ACTH stimulation to adrenal imaging with radioiodocholesterol.
1983 Mar
The relationship of I-131 6 beta-iodomethyl-19-norcholesterol (NP-59) adrenal cortical uptake to indices of androgen secretion in women with hyperandrogenism.
1984 May
The utility of adrenal scintigraphy in Cushing's syndrome and hyperaldosteronism.
1985 Aug
Limited significance of asymmetric adrenal visualization on dexamethasone-suppression scintigraphy.
1985 Jan
The scintigraphic localization of mineralocorticoid-producing adrenocortical carcinoma.
1986 Apr
[Adrenal gland scintigraphy].
1986 Apr
The influence of hypercholesterolaemia on the adrenal uptake and metabolic handling of 131I-6 beta-iodomethyl-19-norcholesterol (NP-59).
1986 Aug
Enterohepatic circulation and distribution of 131I-6 beta-iodomethyl-19-norcholesterol (NP-59).
1986 Aug
Positive iodine-131 6 beta-iodomethyl-19-norcholesterol (NP-59) adrenal images can precede return of adrenocortical function after o,p' DDD treatment.
1988 May
Adrenal localization in the adrenocorticotropic hormone-independent Cushing syndrome.
1988 Oct 1
Distinguishing benign from malignant euadrenal masses.
1988 Oct 15
[Iodo-methyl norcholesterol scintigraphy in the localization of primary hyperaldosteronism].
1989 Jul
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:44:40 GMT 2023
Edited
by admin
on Sat Dec 16 08:44:40 GMT 2023
Record UNII
6B3QJ94C7P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
6-IODOMETHYLCHOLESTEROL
Systematic Name English
I-BIMETROL
Common Name English
CHOLEST-5-EN-3-OL, 6-(IODOMETHYL)-, (3.BETA.)-
Systematic Name English
(3.BETA.)-6-(IODOMETHYL)CHOLEST-5-EN-3-OL
Systematic Name English
(3S,8S,9S,10R,13R,14S,17R)-6-(IODOMETHYL)-10,13-DIMETHYL-17-((2R)-6-METHYLHEPTAN-2-YL)-2,3,4,7,8,9,11,12,14,15,16,17-DODECAHYDRO-1H-CYCLOPENTA(A)PHENANTHREN-3-OL
Systematic Name English
6.BETA.-IODOMETHYL-19-NORCHOLESTEROL
Common Name English
6-.BETA.-IODOMETHYLNORCHOLESTEROL
Common Name English
BIMETROL
Common Name English
Code System Code Type Description
CAS
86522-55-6
Created by admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
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FDA UNII
6B3QJ94C7P
Created by admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
PRIMARY
SMS_ID
100000138945
Created by admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
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EVMPD
SUB79486
Created by admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
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PUBCHEM
21151073
Created by admin on Sat Dec 16 08:44:40 GMT 2023 , Edited by admin on Sat Dec 16 08:44:40 GMT 2023
PRIMARY