2C-B HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H14BrNO2.ClH
Molecular Weight	296.589
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.COC1=CC(Br)=C(OC)C=C1CCN

InChI

InChIKey=UJTWHDAMHSIRDK-UHFFFAOYSA-N

InChI=1S/C10H14BrNO2.ClH/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12;/h5-6H,3-4,12H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	C10H14BrNO2
Molecular Weight	260.128
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2a (5-HT2a) receptor 231 Target ID: CHEMBL322 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16970404	Agonist 2678		27.0 nM [EC50]

PubMed

Title	Date	PubMed
WHO Expert Committee on Drug Dependence. Thirty-second report.	2001	11851193
[A case of acute psychotic episode after a single dose of ecstasy].	2001 Mar-Apr	11407274
Fluorometric determination of DL-fenfluramine, DL-norfenfluramine and phentermine in plasma by achiral and chiral high-performance liquid chromatography.	2001 Nov 5	11710586
Automated headspace solid-phase microextraction and in-matrix derivatization for the determination of amphetamine-related drugs in human urine by gas chromatography-mass spectrometry.	2002 Jan	11866382
In vivo metabolism of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in the rat: identification of urinary metabolites.	2002 Mar	11916016
4-Bromo-2,5-dimethoxyphenethylamine (2C-B): a review of the public domain literature.	2002 Oct-Dec	12632938
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) and structurally related phenylethylamines are potent 5-HT2A receptor antagonists in Xenopus laevis oocytes.	2004 Apr	15006903
Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis.	2004 Mar	15039965
Metabolism of the designer drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in mice, after acute administration.	2004 Nov 25	15522713
A general screening and confirmation approach to the analysis of designer tryptamines and phenethylamines in blood and urine using GC-EI-MS and HPLC-electrospray-MS.	2004 Sep	15516287
Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): analysis of phase I metabolism with hepatocytes of six species including human.	2005 Jan 5	15590110
A study of the metabolism of methamphetamine and 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in isolated rat hepatocytes.	2005 Mar 10	15639607
Optimization of the separation and on-line sample concentration of phenethylamine designer drugs with capillary electrophoresis-fluorescence detection.	2006 Jan 6	16325192
1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists.	2006 Sep 21	16970404
Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines.	2007 Dec	17891159
Studies on the toxicological detection of the designer drug 4-bromo-2,5-dimethoxy-beta-phenethylamine (2C-B) in rat urine using gas chromatography-mass spectrometry.	2007 Feb 1	16978931
Disposition of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) and its metabolite 4-bromo-2-hydroxy-5-methoxyphenethylamine in rats after subcutaneous administration.	2008 Apr 21	18339493
Liquid chromatography-atmospheric pressure ionization electrospray mass spectrometry determination of "hallucinogenic designer drugs" in urine of consumers.	2008 Jun 9	18262381
Metabolism of designer drugs of abuse: an updated review.	2010 Jun 1	20540700
Cerebral vasculopathy after 4-bromo-2,5-dimethoxyphenethylamine ingestion.	2010 May	20445431

Substance Class	Chemical Created by `admin` on `Sat Dec 16 03:28:55 GMT 2023` Edited by `admin` on `Sat Dec 16 03:28:55 GMT 2023`
Record UNII	6AVT4WPN6M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2C-B HYDROCHLORIDE

Common Name

English

2C-B HYDROCHLORIDE [MI]

Common Name

English

BENZENEETHANAMINE, 4-BROMO-2,5-DIMETHOXY-, HYDROCHLORIDE

Systematic Name

English

4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE HYDROCHLORIDE

Systematic Name

English

BENZENEETHANAMINE, 4-BROMO-2,5-DIMETHOXY-, HYDROCHLORIDE (1:1)

Systematic Name

English

2-(2,5-DIMETHOXY-4-BROMOPHENYL)ETHYLAMINE HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

MERCK INDEX

m3180