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Details

Stereochemistry ABSOLUTE
Molecular Formula C17H19NO3
Molecular Weight 285.3377
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NARWEDINE, (+)-

SMILES

[H][C@@]12CC(=O)C=C[C@@]13CCN(C)CC4=CC=C(OC)C(O2)=C34

InChI

InChIKey=QENVUHCAYXAROT-RHSMWYFYSA-N
InChI=1S/C17H19NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,14H,7-10H2,1-2H3/t14-,17-/m1/s1

HIDE SMILES / InChI
Molecular Formula C17H19NO3
Molecular Weight 285.3377
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Narwedine, (+) an isomer of the narwedine (±), the last is the biogenetic precursor of galanthamine, which has been used as a respiratory stimulant.

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Chemoenzymatic Total Synthesis of (+)-Galanthamine and (+)-Narwedine from Phenethyl Acetate.
2016 Oct 4

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:41:41 GMT 2023
Edited
by admin
on Sat Dec 16 05:41:41 GMT 2023
Record UNII
6A3S1D0Z5T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NARWEDINE, (+)-
Common Name English
(+)-GALANTHAMINONE
Common Name English
GALANTHAMINE, 3-DEOXY-3-OXO-, (4A.BETA.,4BS*)-
Common Name English
(+)-NARWEDINE
Common Name English
6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-ONE, 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-, (4AR-(4AR*,8AR*))-
Common Name English
6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-ONE, 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-, (4AR,8AR)-
Common Name English
Code System Code Type Description
FDA UNII
6A3S1D0Z5T
Created by admin on Sat Dec 16 05:41:41 GMT 2023 , Edited by admin on Sat Dec 16 05:41:41 GMT 2023
PRIMARY
CAS
7318-55-0
Created by admin on Sat Dec 16 05:41:41 GMT 2023 , Edited by admin on Sat Dec 16 05:41:41 GMT 2023
PRIMARY
PUBCHEM
441596
Created by admin on Sat Dec 16 05:41:41 GMT 2023 , Edited by admin on Sat Dec 16 05:41:41 GMT 2023
PRIMARY
NIH
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