PYRIPROLE

FC(F)SC1=C(NCC2=NC=CC=C2)N(N=C1C#N)C3=C(Cl)C=C(C=C3Cl)C(F)(F)F

InChIKey=MWMQNVGAHVXSPE-UHFFFAOYSA-N

InChI=1S/C18H10Cl2F5N5S/c19-11-5-9(18(23,24)25)6-12(20)14(11)30-16(28-8-10-3-1-2-4-27-10)15(31-17(21)22)13(7-26)29-30/h1-6,17,28H,8H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
The effect of water and shampooing on the efficacy of a pyriprole 12.5% topical solution against brown dog tick (Rhipicephalus sanguineus) and cat flea (Ctenocephalides felis) infestations on dogs.	2008 Feb 14	18061355
Efficacy of a single application of a 12.5% pyriprole topical solution against laboratory infestations with ticks (Ixodes ricinus, Dermacentor reticulatus, and Rhipicephalus sanguineus) on dogs.	2008 Jul 4	18455315
The effectiveness of a pyriprole (125 mg/ml) and a metaflumizone (150 mg/ml) combined with amitraz (150 mg/ml) spot-on treatment in preventing Phlebotomus perniciosus from feeding on dogs.	2008 Mar	18416253
Efficacy of pyriprole topical solution against the cat flea, Ctenocephalides felis, on dogs.	2008 Spring	18415942
Efficacy of fipronil-(S)-methoprene, metaflumizone combined with amitraz, and pyriprole commercial spot-on products in preventing Culex pipiens pipiens from feeding on dogs.	2009 Aug 1	19648637
Comparative efficacy of two fipronil spot-on formulations against experimental tick infestations (Ixodes ricinus) in dogs.	2010 Aug	20556429
Efficacy of a spot-on formulation of pyriprole on dogs infested with Sarcoptes scabiei.	2010 Sep 18	20852247

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:05:26 GMT 2023` Edited by `admin` on `Fri Dec 15 18:05:26 GMT 2023`
Record UNII	69OX73ZVJN
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

PYRIPROLE

Common Name

English

PYRIPROLE [EMA EPAR VETERINARY]

Common Name

English

PRAC-TIC

Brand Name

English

PYRIPROLE [ISO]

Common Name

English

1-(2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYL)-4-((DIFLUOROMETHYL)THIO)-5-((2-PYRIDINYLMETHYL)AMINO)-1H-PYRAZOLE-3-CARBONITRILE

Systematic Name

English

1-(2,6-DICHLORO-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-P-TOLYL)-4-(DIFLUOROMETHYLTHIO)-5-((2-PYRIDYLMETHYL)AMINO)PYRAZOLE-3-CARBONITRILE

Common Name

English

Classification Tree Code System Code

WHO-VATC

QP53AX26