PYRIPROLE

FC(F)SC1=C(NCC2=CC=CC=N2)N(N=C1C#N)C3=C(Cl)C=C(C=C3Cl)C(F)(F)F

InChIKey=MWMQNVGAHVXSPE-UHFFFAOYSA-N

InChI=1S/C18H10Cl2F5N5S/c19-11-5-9(18(23,24)25)6-12(20)14(11)30-16(28-8-10-3-1-2-4-27-10)15(31-17(21)22)13(7-26)29-30/h1-6,17,28H,8H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Efficacy of a spot-on formulation of pyriprole on dogs infested with Sarcoptes scabiei.	2010-09-18	20852247
Comparative efficacy of two fipronil spot-on formulations against experimental tick infestations (Ixodes ricinus) in dogs.	2010-08	20556429
Efficacy of fipronil-(S)-methoprene, metaflumizone combined with amitraz, and pyriprole commercial spot-on products in preventing Culex pipiens pipiens from feeding on dogs.	2009-08-01	19648637
Efficacy of a single application of a 12.5% pyriprole topical solution against laboratory infestations with ticks (Ixodes ricinus, Dermacentor reticulatus, and Rhipicephalus sanguineus) on dogs.	2008-07-04	18455315
The effectiveness of a pyriprole (125 mg/ml) and a metaflumizone (150 mg/ml) combined with amitraz (150 mg/ml) spot-on treatment in preventing Phlebotomus perniciosus from feeding on dogs.	2008-03	18416253
The effect of water and shampooing on the efficacy of a pyriprole 12.5% topical solution against brown dog tick (Rhipicephalus sanguineus) and cat flea (Ctenocephalides felis) infestations on dogs.	2008-02-14	18061355
Efficacy of pyriprole topical solution against the cat flea, Ctenocephalides felis, on dogs.	2008	18415942

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:02:16 GMT 2025` Edited by `admin` on `Mon Mar 31 19:02:16 GMT 2025`
Record UNII	69OX73ZVJN
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

PYRIPROLE

Common Name

English

1-(2,6-DICHLORO-.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-P-TOLYL)-4-(DIFLUOROMETHYLTHIO)-5-((2-PYRIDYLMETHYL)AMINO)PYRAZOLE-3-CARBONITRILE

Preferred Name

English

PYRIPROLE [EMA EPAR VETERINARY]

Common Name

English

PRAC-TIC

Brand Name

English

PYRIPROLE [ISO]

Common Name

English

1-(2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYL)-4-((DIFLUOROMETHYL)THIO)-5-((2-PYRIDINYLMETHYL)AMINO)-1H-PYRAZOLE-3-CARBONITRILE

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QP53AX26