U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C21H25NO4.ClH
Molecular Weight 391.888
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLAUCINE HYDROCHLORIDE

SMILES

Cl.[H][C@]12CC3=CC(OC)=C(OC)C=C3C4=C1C(CCN2C)=CC(OC)=C4OC

InChI

InChIKey=KRMYOICRUJJKEZ-RSAXXLAASA-N
InChI=1S/C21H25NO4.ClH/c1-22-7-6-12-9-18(25-4)21(26-5)20-14-11-17(24-3)16(23-2)10-13(14)8-15(22)19(12)20;/h9-11,15H,6-8H2,1-5H3;1H/t15-;/m0./s1

HIDE SMILES / InChI

Molecular Formula C21H25NO4
Molecular Weight 355.4275
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Central action of glaucine in rodents.
1994
Geographic distribution of three alkaloid chemotypes of Croton lechleri.
2002 Jun
Effects of some antioxidative aporphine derivatives on striatal dopaminergic transmission and on MPTP-induced striatal dopamine depletion in B6CBA mice.
2003 Feb
Behavioural evidence of agonist-like effect of isoteoline at 5-HT1B serotonergic receptors in mice.
2003 Jan
[Resource investigation and quality evaluation on wild Corydalis yanhusuo].
2004 May
Photochemistry of phytoalexins containing phenalenone-like chromophores: photophysics and singlet oxygen photosensitizing properties of the plant oxoaporphine alkaloid oxoglaucine.
2005 Jan-Feb
A novel alkaloid from Mitrephora maingayi.
2005 Jun
Identification and quantification of isoquinoline alkaloids in the genus Sarcocapnos by GC-MS.
2005 Sep-Oct
Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities.
2008 Aug 1
Michaelis-Menten kinetic analysis of drugs of abuse to estimate their affinity to human P-glycoprotein.
2013 Feb 27
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 01:47:05 GMT 2023
Edited
by admin
on Sat Dec 16 01:47:05 GMT 2023
Record UNII
69444SR62I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLAUCINE HYDROCHLORIDE
WHO-DD  
Common Name English
O,O-DIMETHYLBOLDINE HYDROCHLORIDE
Common Name English
(6AS)-5,6,6A,7-TETRAHYDRO-1,2,9,10-TETRAMETHOXY-6-METHYL-4H-DIBENZO(DE,G)QUINOLINE HYDROCHLORIDE
Common Name English
Glaucine hydrochloride [WHO-DD]
Common Name English
(+)-GLAUCINE HYDROCHLORIDE
Common Name English
Code System Code Type Description
CAS
2269-06-9
Created by admin on Sat Dec 16 01:47:05 GMT 2023 , Edited by admin on Sat Dec 16 01:47:05 GMT 2023
PRIMARY
EPA CompTox
DTXSID40945360
Created by admin on Sat Dec 16 01:47:05 GMT 2023 , Edited by admin on Sat Dec 16 01:47:05 GMT 2023
PRIMARY
PUBCHEM
16753
Created by admin on Sat Dec 16 01:47:05 GMT 2023 , Edited by admin on Sat Dec 16 01:47:05 GMT 2023
PRIMARY
ECHA (EC/EINECS)
218-869-1
Created by admin on Sat Dec 16 01:47:05 GMT 2023 , Edited by admin on Sat Dec 16 01:47:05 GMT 2023
PRIMARY
FDA UNII
69444SR62I
Created by admin on Sat Dec 16 01:47:05 GMT 2023 , Edited by admin on Sat Dec 16 01:47:05 GMT 2023
PRIMARY
SMS_ID
100000078187
Created by admin on Sat Dec 16 01:47:05 GMT 2023 , Edited by admin on Sat Dec 16 01:47:05 GMT 2023
PRIMARY
EVMPD
SUB13974MIG
Created by admin on Sat Dec 16 01:47:05 GMT 2023 , Edited by admin on Sat Dec 16 01:47:05 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY