Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 11:47:43 GMT 2023
by
admin
on
Sat Dec 16 11:47:43 GMT 2023
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
68L32FM3IQ
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
P10828
Created by
admin on Sat Dec 16 11:47:43 GMT 2023 , Edited by admin on Sat Dec 16 11:47:43 GMT 2023
|
PRIMARY | |||
|
68L32FM3IQ
Created by
admin on Sat Dec 16 11:47:43 GMT 2023 , Edited by admin on Sat Dec 16 11:47:43 GMT 2023
|
PRIMARY | |||
|
P10828
Created by
admin on Sat Dec 16 11:47:43 GMT 2023 , Edited by admin on Sat Dec 16 11:47:43 GMT 2023
|
PRIMARY |
| Linkage Type | Residue Index | |
|---|---|---|
| ZINC FINGER | 1_107 | 1_127 |
| ZINC FINGER | 1_145 | 1_169 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
AGONIST -> TARGET |
Binds selectively to the main hepatic form of thyroid hormone (TH) receptor, TRβ1, compared to TRα1, which is principally responsible for thyrotoxic effects on heart, muscle and bone.
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AGONIST -> TARGET |
increased expression of the hepatic LDL-receptor gene
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AGONIST -> TARGET | |||
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AGONIST -> TARGET |
28 times more selective to TR.beta. than TR.alpha.
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AGONIST -> TARGET | |||
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AGONIST -> TARGET |
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AGONIST -> TARGET |
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MIMETIC->TARGET | |||
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AGONIST -> TARGET |
Increased ABCD2 gene expression by 10-fold in X-ALD fibroblasts (4 nm)
EC50
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|