AVE-0991

Details

Stereochemistry	ACHIRAL
Molecular Formula	C29H32N4O5S2
Molecular Weight	580.718
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCNC(=O)NS(=O)(=O)C1=C(C=C(CC(C)C)S1)C2=CC=C(CN3C(C=O)=C(OC)N=C3C4=CC=CC=C4)C=C2

InChI

InChIKey=QTOZBSNPDCWHPV-UHFFFAOYSA-N

InChI=1S/C29H32N4O5S2/c1-5-30-29(35)32-40(36,37)28-24(16-23(39-28)15-19(2)3)21-13-11-20(12-14-21)17-33-25(18-34)27(38-4)31-26(33)22-9-7-6-8-10-22/h6-14,16,18-19H,5,15,17H2,1-4H3,(H2,30,32,35)

HIDE SMILES / InChI

Molecular Formula	C29H32N4O5S2
Molecular Weight	580.718
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Proto-oncogene Mas 3 Target ID: P12526 Gene ID: 25153.0 Gene Symbol: Mas1 Target Organism: Rattus norvegicus (Rat) Sources: https://www.ncbi.nlm.nih.gov/pubmed/15326087	Agonist 2678		47.5 nM [IC50]

PubMed

Title	Date	PubMed
Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.	2004 Oct	15326087

Substance Class	Chemical Created by `admin` on `Sat Dec 16 00:01:37 GMT 2023` Edited by `admin` on `Sat Dec 16 00:01:37 GMT 2023`
Record UNII	68JR6NCI7I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AVE-0991

Common Name

English

2-THIOPHENESULFONAMIDE, N-((ETHYLAMINO)CARBONYL)-3-(4-((5-FORMYL-4-METHOXY-2-PHENYL-1H-IMIDAZOL-1-YL)METHYL)PHENYL)-5-(2-METHYLPROPYL)-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID50184526

Created by admin on Sat Dec 16 00:01:37 GMT 2023 , Edited by admin on Sat Dec 16 00:01:37 GMT 2023

PRIMARY

FDA UNII

68JR6NCI7I

Created by admin on Sat Dec 16 00:01:37 GMT 2023 , Edited by admin on Sat Dec 16 00:01:37 GMT 2023

PRIMARY

PUBCHEM

9851724

Created by admin on Sat Dec 16 00:01:37 GMT 2023 , Edited by admin on Sat Dec 16 00:01:37 GMT 2023

PRIMARY

CAS

304462-19-9

Created by admin on Sat Dec 16 00:01:37 GMT 2023 , Edited by admin on Sat Dec 16 00:01:37 GMT 2023

PRIMARY

Related Record Type Details


					68JR6NCI7I

AVE-0991

ACTIVE MOIETY