Thorium oxalate

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C2O4.Th
Molecular Weight	408.0761
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Th+4].[O-]C(=O)C([O-])=O.[O-]C(=O)C([O-])=O

InChI

InChIKey=VCXNHCBXRKRKSO-UHFFFAOYSA-J

InChI=1S/2C2H2O4.Th/c2*3-1(4)2(5)6;/h2*(H,3,4)(H,5,6);/q;;+4/p-4

HIDE SMILES / InChI

Molecular Formula	C2O4
Molecular Weight	88.019
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Th
Molecular Weight	232.0381
Charge	4
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20318815 | https://www.ncbi.nlm.nih.gov/pubmed/17890786

Thorium dioxide, a main component of Thorotrast that was used as a contrast agent for cerebral angiography. Thorotrast is an alpha emitter and primary site of deposition is the reticuloendothelial system including the liver, spleen, bone marrow, and lymph nodes. However was discovered, that this compound can cause hepatic angiosarcoma with a long latent period. That is why this contrast agent was withdrawn.

Approval Year

PubMed

Title	Date	PubMed
Hepatic angiosarcoma associated with androgenic-anabolic steroids.	1979 Nov 24	91848
Alteration of the c-fms gene in a blood sample from a Thorotrast individual.	1992 Jul	1522006
p53 mutations in primary hepatic angiosarcomas not associated with vinyl chloride exposure.	1995 Nov	7586214

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 12:58:29 GMT 2023` Edited by `admin` on `Sat Dec 16 12:58:29 GMT 2023`
Record UNII	68C5PQN2GF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Thorium oxalate

Systematic Name

English

(T-4)-Bis[ethanedioato(2-)-κO1,κO2]thorium

Systematic Name

English

Thorium(4+) oxalate

Common Name

English

Thorium, bis[ethanedioato(2-)-κO1,κO2]-, (T-4)-

Systematic Name

English

NSC-112248

Code

English

Oxalic acid, thorium(4+) salt (2:1)

Systematic Name

English

Thorium(4+) bis(oxalate)

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

218-038-3