Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C21H20N6O |
| Molecular Weight | 372.4231 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C=C[C@H](C[C@@H]1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N
InChI
InChIKey=TYBYEUBYYCLFNN-VQIMIIECSA-N
InChI=1S/C21H20N6O/c1-27-11-10-16(24-21(28)23-15-8-6-14(13-22)7-9-15)12-19(27)20-25-17-4-2-3-5-18(17)26-20/h2-11,16,19H,12H2,1H3,(H,25,26)(H2,23,24,28)/t16-,19-/m1/s1
| Molecular Formula | C21H20N6O |
| Molecular Weight | 372.4231 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:54:56 UTC 2023
by
admin
on
Sat Dec 16 14:54:56 UTC 2023
|
| Record UNII |
68AY89Y84D
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Systematic Name | English | ||
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| Code System | Code | Type | Description | ||
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155804785
Created by
admin on Sat Dec 16 14:54:56 UTC 2023 , Edited by admin on Sat Dec 16 14:54:56 UTC 2023
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PRIMARY | PUBCHEM | ||
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68AY89Y84D
Created by
admin on Sat Dec 16 14:54:56 UTC 2023 , Edited by admin on Sat Dec 16 14:54:56 UTC 2023
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PRIMARY | |||
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2222533-65-3
Created by
admin on Sat Dec 16 14:54:56 UTC 2023 , Edited by admin on Sat Dec 16 14:54:56 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE |
Glasdegib was the most abundant circulating component in plasma, constituting 69% of plasma radioactivity, with minor circulating metabolites each being <8% of radioactivity.
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