Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C25H30F3N3O4 |
| Molecular Weight | 493.5186 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H](CC1=CC(C(N)=O)=C2N(CCCO)C=CC2=C1)NCCOC3=CC=CC=C3OCC(F)(F)F
InChI
InChIKey=VICSLOHTZDWOFF-QGZVFWFLSA-N
InChI=1S/C25H30F3N3O4/c1-17(30-8-12-34-21-5-2-3-6-22(21)35-16-25(26,27)28)13-18-14-19-7-10-31(9-4-11-32)23(19)20(15-18)24(29)33/h2-3,5-7,10,14-15,17,30,32H,4,8-9,11-13,16H2,1H3,(H2,29,33)/t17-/m1/s1
| Molecular Formula | C25H30F3N3O4 |
| Molecular Weight | 493.5186 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
KMD-3241 (Dehydro Silodosin) is a silodosin metabolite (also known as an impurity of Silodosin). Silodosin is a selective antagonsit of alpha-1a adrenergic receptor which was developed by Kissei Pharmaceutical and approved by FDA under the name Rapaflo for the treatment of signs and symptoms associated with benign prostatic hyperplasia. The affnities of silodosin metabolites, KMD-3241, KMD-3289 and
KMD-3295, for alpha1A-AR subtype receptor were equal to or lower than that of silodosin.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:27:06 GMT 2025
by
admin
on
Mon Mar 31 23:27:06 GMT 2025
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| Record UNII |
6787MV7QU0
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| Record Status |
Validated (UNII)
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| Record Version |
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9891871
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6787MV7QU0
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DTXSID20432445
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175870-21-0
Created by
admin on Mon Mar 31 23:27:06 GMT 2025 , Edited by admin on Mon Mar 31 23:27:06 GMT 2025
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| Related Record | Type | Details | ||
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