2-PYRIDONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H5NO
Molecular Weight	95.0995
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1NC=CC=C1

InChI

InChIKey=UBQKCCHYAOITMY-UHFFFAOYSA-N

InChI=1S/C5H5NO/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)

HIDE SMILES / InChI

Molecular Formula	C5H5NO
Molecular Weight	95.0995
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Conformationally rigid chelate rings in metal complexes of pyridyloxy-substituted 2,2'-dioxybiphenyl-cyclotetra- and cyclotriphosphazene platforms.	2007-11-12	17949082
Cytostatic evaluations of nucleoside analogs related to unnatural base pairs for a genetic expansion system.	2007-10-15	17804231
Discovery of novel and orally active NR2B-selective N-methyl-D-aspartate (NMDA) antagonists, pyridinol derivatives with reduced HERG binding affinity.	2007-10-15	17768047
Role of guiding groups in cinchona-modified platinum for controlling the sense of enantiodifferentiation in the hydrogenation of ketones.	2007-08-29	17676845
Photolytic (UVC) and photocatalyic (UVC/TiO2) decomposition of pyridines.	2007-07-31	17544577
The iromycins, a new family of pyridone metabolites from Streptomyces sp. I. Structure, NOS inhibitory activity, and biosynthesis.	2007-07-06	17564461
Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors.	2007-07-01	17449248
Hierarchy of supramolecular synthons: persistent hydroxyl...pyridine hydrogen bonds in cocrystals that contain a cyano acceptor.	2007-05-16	17500564
Improved determination of structural changes of 2-pyridone-(H2O)1 upon electronic excitation.	2007-05-03	17419594
Synthesis of carbamates and ureas using Zr(IV)-catalyzed exchange processes.	2007-04-12	17358074
Excited-state intramolecular proton transfer in 2-(3'-hydroxy-2'-pyridyl)benzoxazole. Evidence of coupled proton and charge transfer in the excited state of some o-hydroxyarylbenzazoles.	2007-03-15	17309239
Use of SPE-GC/EIMS for residue analysis in wine elaborated from musts spiked with formulations of chlorpyriphos-methyl, methiocarb, dicofol, and cyproconazol.	2007-03	17444223
Cu-catalyzed N- and O-arylation of 2-, 3-, and 4-hydroxypyridines and hydroxyquinolines.	2007-02-15	17286371
Carbonarones A and B, new bioactive gamma-Pyrone and alpha-Pyridone derivatives from the marine-derived fungus Aspergillus carbonarius.	2007-02	17420566
How resonance assists hydrogen bonding interactions: an energy decomposition analysis.	2007-01-15	17143867
Ligand-promoted dehydrogenation of alcohols catalyzed by Cp*Ir complexes. A new catalytic system for oxidant-free oxidation of alcohols.	2007-01-04	17192097
Thrombin inhibitors with novel P1 binding pocket functionality: free energy of binding analysis.	2007-01	17013633
Studies on the activity of three palladium(II) compounds of the form: trans-PdL2Cl2 where L=2-hydroxypyridine, 3-hydroxypyridine, and 4-hydroxypyridine.	2007-01	16997377
ADDP and PS-PPh3: an efficient Mitsunobu protocol for the preparation of pyridine ether PPAR agonists.	2006-10-31	17076898
New modular and efficient approach to 6-substituted pyridin-2-yl C-nucleosides.	2006-09-15	16958526
Selective cleavage of heparin using aqueous 2-hydroxypyridine: production of an aldose-terminating fragment with high anticoagulant activity.	2006-08-04	16781674
2-hydroxypyridine <--> 2-pyridone tautomerization: catalytic influence of formic acid.	2006-07-27	16854025
Gas-phase Watson-Crick and Hoogsteen isomers of the nucleobase mimic 9-methyladenine x 2-pyridone.	2006-07-17	16755637
An approach to helical tubular self-aggregation using C2-symmetric self-complementary hydrogen-bonding cavity molecules.	2006-06-28	16787092
Boxes, helicates, and coordination polymers: a structural and magnetochemical investigation of the diverse coordination chemistry of simple pyridine-alcohol ligands.	2006-06-12	16749821
Di- and trinuclear complexes derived from hexakis(2-pyridyloxy)cyclotriphosphazene. Unusual P-O bond cleavage in the formation of [{(L'CuCl)2(Co(NO3)}Cl] (L' = N3P3(OC5H4N)5(O)).	2006-05-01	16634581
Synthesis and SAR of highly potent and selective dopamine D3-receptor antagonists: variations on the 1H-pyrimidin-2-one theme.	2006-04-01	16439127
Isomerization reaction of head-to-head alpha-pyridonato-bridged ethylenediaminepalladium(II) binuclear complex, [Pd2(en)2(C5H4NO)2]2+, in aqueous solution.	2006-03-28	16538268
Studies on the synthesis, characterization, binding with DNA and activities of two cis-planaramineplatinum(II) complexes of the form: cis-PtL(NH3)Cl2 where L = 3-hydroxypyridine and 2,3-diaminopyridine.	2006-03-13	16533399
Chemical hybridizing agents for chickpea (Cicer arietinum L.): leads from QSAR analysis of ethyl oxanilates and pyridones.	2006-03-08	16506846
Hydroxy- and mercaptopyridine pincer platinum and palladium complexes generated by silver-free halide abstraction.	2006-03-06	16499365
Interaction of thioamides, selenoamides, and amides with diiodine.	2006	17497011
Site-specific fluorescent labeling of RNA molecules by specific transcription using unnatural base pairs.	2005-12-14	16332078
Di-mu-formato-1kappa2O:2kappa2O'-di-mu-pyridin-2-olato-1kappaO:2kappaN;1kappaN:2kappaO-bis[(2-pyridone-kappaO)copper(II)] acetonitrile 1.02-solvate.	2005-12	16330838
Two competitive routes in the lactim-lactam phototautomerization of a hydroxypyridine derivative cation in water: dissociative mechanism versus water-assisted proton transfer.	2005-11-17	16833311
Copper(II) chloride complexes with multimodal ligands based on the cyclotriphosphazene platform.	2005-10-21	16193152
Routes to unique palladium A-frame complexes with a bridging fluoro-ligand.	2005-10-21	16193151
Palladium-catalyzed carbonylation of yne esters leading to gamma-alkylidene alpha,beta-unsaturated gamma-lactones.	2005-09-29	16178539
Insights into structure-activity relationships from lipophilicity profiles of pyridin-2(1H)-one analogs of the cardiotonic agent milrinone.	2005-09	15955679
Communication and re-use of chemical information in bioscience.	2005-07-18	16026614
An efficient unnatural base pair for a base-pair-expanded transcription system.	2005-06-22	15954770
6-Methyl-2-pyridone: an elusive structure finally solved.	2005-06	15930691
Theoretical studies of proton-transfer reactions of 2-hydroxypyridine--(H2O)n (n = 0-2) in the ground and excited states.	2005-05-05	16833720
Dielectric dispersion in water + 2-hydroxypyridine solid mixtures.	2005-03-31	16851577
Density functional study on the reaction mechanism of proton transfer in 2-pyridone: effect of hydration and self-association.	2005-02-24	16833466
Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors.	2005-02-15	15686946
Site-specific incorporation of fluorescent probes into RNA by specific transcription using unnatural base pairs.	2005	17150746
The versatile, efficient, and stereoselective self-assembly of transition-metal helicates by using hydrogen-bonds.	2004-12-17	15551322
The Lycopodium alkaloids.	2004-12	15565253
Site-specific fluorescent labeling of RNA by a base-pair expanded transcription system.	2004	17150465

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:46:26 GMT 2025` Edited by `admin` on `Mon Mar 31 18:46:26 GMT 2025`
Record UNII	6770O3A2I5
Record Status	`FAILED`
Record Version

Download

Name

Type

Language

2-PYRIDONE

Systematic Name

English

NSC-172522

Preferred Name

English

2-HYDROXYPYRIDINE

Systematic Name

English

2-PYRIDINOL

Systematic Name

English

2(1H)-PYRIDONE

Systematic Name

English

LEVETIRACETAM IMPURITY C [EP IMPURITY]

Common Name

English

2-PYRIDINONE

Systematic Name

English

PYRIDIN-2-ONE

Systematic Name

English

LEVETIRACETAM IMPURITY, PYRIDIN-2-OL- [USP IMPURITY]

Common Name

English

PYRIDIN-2-OL

Systematic Name

English

2(1H)-PYRIDINONE

Systematic Name

English

HYDROXYPYRIDINE, 2-

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

205-520-3