CYCLOCREATINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H9N3O2
Molecular Weight	143.1439
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CN1CCNC1=N

InChI

InChIKey=AMHZIUVRYRVYBA-UHFFFAOYSA-N

InChI=1S/C5H9N3O2/c6-5-7-1-2-8(5)3-4(9)10/h1-3H2,(H2,6,7)(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C5H9N3O2
Molecular Weight	143.1439
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/22751104 | https://www.ncbi.nlm.nih.gov/pubmed/7850923 | https://www.ncbi.nlm.nih.gov/pubmed/8042860 | https://www.ncbi.nlm.nih.gov/pubmed/9412496

Cyclocreatine is a nearly planar creatine analog. Cyclocreatine is an efficient substrate for creatine kinase, but its phosphorylated form is a poor phosphate donor in comparison with creatine phosphate. It exerts antitumor, antiviral, neuroprotective activity.

CNS Activity

Approval Year

PubMed

Title	Date	PubMed
Elevated creatine kinase activity in primary hepatocellular carcinoma.	2005-03-05	15748292
Cyclocreatine (1-carboxymethyl-2-iminoimidazolidine) inhibits the replication of human herpes viruses.	1994-04	8042860

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:01:15 GMT 2025` Edited by `admin` on `Mon Mar 31 18:01:15 GMT 2025`
Record UNII	6732XGX1RK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

2-IMINO-1-IMIDAZOLIDINEACETIC ACID

Preferred Name

English

CYCLOCREATINE

Common Name

English

NSC-707961

Code

English

AM-285

Code

English

1-CARBOXYMETHYL-2-IMINO-IMIDAZOLIDINE

Systematic Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/16/1676