U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H9N3.2ClH
Molecular Weight 184.067
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BETAZOLE HYDROCHLORIDE

SMILES

Cl.Cl.NCCC1=NNC=C1

InChI

InChIKey=BUXCUOWXTOKEMQ-UHFFFAOYSA-N
InChI=1S/C5H9N3.2ClH/c6-3-1-5-2-4-7-8-5;;/h2,4H,1,3,6H2,(H,7,8);2*1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H9N3
Molecular Weight 111.1451
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

BETAZOLE is a histamine H2 receptor agonist used clinically to test gastric secretory function.

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Histalog

Approved Use

For use clinically to test gastric secretory function.

Launch Date

1952
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG

OverviewOther

Other InhibitorOther SubstrateOther Inducer

Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
yes
PubMed

PubMed

TitleDatePubMed
Detection of achlorhydria by tubeless gastric analysis with betazole hydrochloride as the gastric stimulant.
1959 Sep 10
The effect of intravenous histalog on gastric secretion in man.
1967 Nov
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:22:34 GMT 2023
Edited
by admin
on Fri Dec 15 15:22:34 GMT 2023
Record UNII
66ABP6C83F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BETAZOLE HYDROCHLORIDE
JAN   ORANGE BOOK   USP-RS   WHO-DD  
Common Name English
BETAZOLE HCL
Common Name English
1H-PYRAZOLE-3-ETHANAMINE, DIHYDROCHLORIDE
Common Name English
NSC-759872
Code English
3-(2-Aminoethyl)pyrazole dihydrochloride
Systematic Name English
HISTALOG
Brand Name English
BETAZOLE HYDROCHLORIDE [JAN]
Common Name English
BETAZOLE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
BETAZOLE DIHYDROCHLORIDE
MI  
Common Name English
BETAZOLE DIHYDROCHLORIDE [MI]
Common Name English
Betazole hydrochloride [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1937
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL1201323
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
EPA CompTox
DTXSID6047789
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
CHEBI
31280
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
DRUG BANK
DBSALT000898
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
CAS
138-92-1
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
NSC
759872
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
ECHA (EC/EINECS)
205-345-2
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
MERCK INDEX
m2455
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY Merck Index
PUBCHEM
67412
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
EVMPD
SUB00789MIG
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
FDA UNII
66ABP6C83F
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
NCI_THESAURUS
C65259
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
SMS_ID
100000085005
Created by admin on Fri Dec 15 15:22:34 GMT 2023 , Edited by admin on Fri Dec 15 15:22:34 GMT 2023
PRIMARY
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