Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C7H13N3O4.H2O |
| Molecular Weight | 221.2111 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.NCC(=O)N[C@@H](CCC(N)=O)C(O)=O
InChI
InChIKey=KLFWVRQACSYLOH-WCCKRBBISA-N
InChI=1S/C7H13N3O4.H2O/c8-3-6(12)10-4(7(13)14)1-2-5(9)11;/h4H,1-3,8H2,(H2,9,11)(H,10,12)(H,13,14);1H2/t4-;/m0./s1
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C7H13N3O4 |
| Molecular Weight | 203.1958 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A novel inhibitor of the mammalian peptide transporter PEPT1. | 2001 Apr 10 |
|
| Postoperative glycyl-glutamine infusion reduces immunosuppression: partial prevention of the surgery induced decrease in HLA-DR expression on monocytes. | 2001 Feb |
|
| Influence of glutamine and glycyl-glutamine on in vitro lymphocyte proliferation in children with solid tumors. | 2001 Jun |
|
| Inhibition of interleukin-1beta and prostaglandin E(2) thermogenesis by glycyl-glutamine, a pro-opiomelanocortin-derived peptide. | 2001 Mar 16 |
|
| No evidence for active peptide transport in forestomach epithelia of sheep. | 2001 Oct |
|
| Bidirectional electrogenic transport of peptides by the proton-coupled carrier PEPT1 in Xenopus laevis oocytes: its asymmetry and symmetry. | 2001 Oct 15 |
|
| Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1. | 2001 Sep |
|
| Characteristics of lysophosphatidylcholine in its inhibition of taurine uptake by human intestinal Caco-2 cells. | 2002 Apr |
|
| Renal assimilation of short chain peptides: visualization of tubular peptide uptake. | 2002 Aug |
|
| Glycyl-glutamine-supplemented long-term total parenteral nutrition selectively improves structure and function in heterotopic small-bowel autotransplantation in the pig. | 2003 Dec |
|
| Characterisation of intestinal peptide transporter of the Antarctic haemoglobinless teleost Chionodraco hamatus. | 2003 Feb |
|
| Perioperative GLY-GLN infusion diminishes the surgery-induced period of immunosuppression: accelerated restoration of the lipopolysaccharide-stimulated tumor necrosis factor-alpha response. | 2003 Jan |
|
| Choline potentiates the pressor response evoked by glycyl-glutamine or naloxone in haemorrhaged rats. | 2003 Sep |
|
| Enhanced effect of glycyl-L-glutamine on mouse preimplantation embryos in vitro. | 2004 Jul |
|
| Direct visualization of peptide uptake activity in the central nervous system of the rat. | 2004 Jun 24 |
|
| Randomized, double-blind, controlled study of glycyl-glutamine-dipeptide in the parenteral nutrition of patients with acute leukemia undergoing intensive chemotherapy. | 2004 Mar |
|
| Glycyl-L-glutamine disposition in rat choroid plexus epithelial cells in primary culture: role of PEPT2. | 2005 Aug |
|
| Mouse embryo development following IVF in media containing either L-glutamine or glycyl-L-glutamine. | 2005 May |
|
| Glycyl-glutamine, an endogenous beta-endorphin-derived peptide, inhibits morphine-induced conditioned place preference, tolerance, dependence, and withdrawal. | 2005 Nov |
|
| Glycyl-glutamine in nucleus accumbens reduces ethanol intake in alcohol preferring (P) rats. | 2005 Oct 5 |
|
| Functional expression of the peptide transporter PEPT2 in the mammalian enteric nervous system. | 2005 Sep 12 |
|
| High-affinity peptide transporter PEPT2 (SLC15A2) of the zebrafish Danio rerio: functional properties, genomic organization, and expression analysis. | 2006 Feb 14 |
|
| Glycyl-glutamine inhibits nicotine conditioned place preference and withdrawal. | 2006 Jan 13 |
|
| The effect of glutamine-supplemented total parenteral nutrition on nutrition and intestinal absorptive function in a rat model. | 2006 Jun |
|
| Enteral feeding of glycyl-glutamine dipeptide improves the structure and absorptive function of the small intestine after allogenetic liver transplantation in rats. | 2006 May |
|
| [Protective effects of glycyl-glutamine dipeptide supplement on the heart function in burn rats]. | 2007 Aug |
|
| Synthesis and characterization of complex of glycyl-L-glutamine and bismuth trichloride. | 2008 |
|
| Characterisation of electrogenic nutrient absorption in the Cftr TgH(neoim)Hgu mouse model. | 2008 Aug |
|
| Glycyl-glutamine reduces ethanol intake at three reward sites in P rats. | 2008 Mar |
|
| Cyclo-glycyl-glutamine inhibits ethanol intake in P and Sprague-Dawley rats. | 2008 Mar |
|
| Substrate-induced changes in the density of peptide transporter PEPT1 expressed in Xenopus oocytes. | 2008 Nov |
|
| Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity, and immune responses of weaning piglets challenged with lipopolysaccharide. | 2009 Dec |
|
| Inhibition of intracellular dipeptide hydrolysis uncovers large outward transport currents of the peptide transporter PEPT1 in Xenopus oocytes. | 2009 Feb |
|
| Electrophysiological characterization of electrolyte and nutrient transport across the small intestine in horses. | 2009 Jun |
|
| Amino acids - Guidelines on Parenteral Nutrition, Chapter 4. | 2009 Nov 18 |
|
| Glycyl-glutamine (beta-endorphin(30-31)) inhibits morphine-induced dopamine efflux in the nucleus accumbens. | 2010 May |
|
| Mammalian oocytes are targets for prostaglandin E2 (PGE2) action. | 2010 Nov 1 |
|
| The impact of glutamine dipeptide-supplemented parenteral nutrition on outcomes of surgical patients: a meta-analysis of randomized clinical trials. | 2010 Sep-Oct |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:17:20 GMT 2023
by
admin
on
Sat Dec 16 09:17:20 GMT 2023
|
| Record UNII |
668A00JUHO
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
24820180
Created by
admin on Sat Dec 16 09:17:20 GMT 2023 , Edited by admin on Sat Dec 16 09:17:20 GMT 2023
|
PRIMARY | |||
|
SUB32320
Created by
admin on Sat Dec 16 09:17:20 GMT 2023 , Edited by admin on Sat Dec 16 09:17:20 GMT 2023
|
PRIMARY | |||
|
172669-64-6
Created by
admin on Sat Dec 16 09:17:20 GMT 2023 , Edited by admin on Sat Dec 16 09:17:20 GMT 2023
|
PRIMARY | |||
|
DTXSID90647443
Created by
admin on Sat Dec 16 09:17:20 GMT 2023 , Edited by admin on Sat Dec 16 09:17:20 GMT 2023
|
PRIMARY | |||
|
668A00JUHO
Created by
admin on Sat Dec 16 09:17:20 GMT 2023 , Edited by admin on Sat Dec 16 09:17:20 GMT 2023
|
PRIMARY | |||
|
100000127132
Created by
admin on Sat Dec 16 09:17:20 GMT 2023 , Edited by admin on Sat Dec 16 09:17:20 GMT 2023
|
PRIMARY | |||
|
211446-46-7
Created by
admin on Sat Dec 16 09:17:20 GMT 2023 , Edited by admin on Sat Dec 16 09:17:20 GMT 2023
|
NON-SPECIFIC STOICHIOMETRY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ANHYDROUS->SOLVATE |
