Samatatug

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 13:18:30 GMT 2025` Edited by `admin` on `Wed Apr 02 13:18:30 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	6656J6CPP2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

XB-002 MAB

Preferred Name

English

Samatatug

Official Name

English

Immunoglobulin G1 [de-C-terminal-lysine], anti-(human blood-coagulation factor III) (human monoclonal XB002 ?1-chain), disulfide with human monoclonal XB002 ?-chain, dimer

Common Name

English

H-gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV1-18*01 (94.9%) -(IGHD) -IGHJ3*01 (92.3%) M123>T (118), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (220) (124

Common Name

English

samatatug [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens F3 (coagulation factor III (thromboplastin, tissue factor), CD142)], Homo sapiens monoclonal antibody

Common Name

English

Code System Code Type Description

SMS_ID

300000045047

Created by admin on Wed Apr 02 13:18:30 GMT 2025 , Edited by admin on Wed Apr 02 13:18:30 GMT 2025

PRIMARY

CAS

2861288-57-3

Created by admin on Wed Apr 02 13:18:30 GMT 2025 , Edited by admin on Wed Apr 02 13:18:30 GMT 2025

PRIMARY

NCI_THESAURUS

C206984

Created by admin on Wed Apr 02 13:18:30 GMT 2025 , Edited by admin on Wed Apr 02 13:18:30 GMT 2025

PRIMARY

INN

12921

Created by admin on Wed Apr 02 13:18:30 GMT 2025 , Edited by admin on Wed Apr 02 13:18:30 GMT 2025

PRIMARY

FDA UNII

6656J6CPP2

Created by admin on Wed Apr 02 13:18:30 GMT 2025 , Edited by admin on Wed Apr 02 13:18:30 GMT 2025

PRIMARY

From	To
4_135	4_195
4_23	4_88
3_135	3_195
3_23	3_88
2_373	2_431
2_267	2_327
2_226	4_215
2_150	2_206
2_22	2_96
1_373	1_431
1_267	1_327
1_235	2_235
1_232	2_232
1_226	3_215
1_150	1_206
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_303
N	2_303

Related Record Type Details


					6656J6CPP2

Samatatug

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	Q		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL